ABSTRACT
Objetivo: Avaliar o perfil da prática de atividade física (AF) e de fisioterapia em indivíduos com doença de Parkinson (DP). Métodos: Pacientes foram recrutados a partir de dois centros de desordens de movimento de Belo Horizonte (Ambulatório Bias Fortes da Universidade Federal de Minas Gerais e Centro Metropolitano de Especialidades Médicas da Santa Casa de Belo Horizonte) entre fevereiro a dezembro de 2019. Resultados: Cento e oitenta e cinco indivíduos responderam um questionário para coleta de dados sociodemográficos, história médica e prática de AF e/ou fisioterapia. Ao comparar os indivíduos dos dois centros, houve diferença apenas em relação à frequência de comorbidades. A hipertensão arterial foi a comorbidade mais comum. Apenas 37,8% e 20,5% dos indivíduos relataram praticar AF ou fazer fisioterapia, respectivamente. A caminhada foi a atividade física mais comum. Pacientes sedentários tinham idade mais avançada, menor tempo de escolaridade, maior duração da DP, e eram mais acometidos por outras comorbidades quando comparados aos pacientes mais ativos. Conclusão: O presente estudo mostra a influência da idade, da escolaridade e do tempo de DP na adesão à prática de AF e fisioterapia. Iniciativas de saúde pública são necessárias para promover a mudança de comportamento e melhorar as oportunidades de AF entre os indivíduos com DP
Objective: The present study aimed to evaluate the profile of physical activity (PA) and physical therapy in individuals with Parkinson's disease (PD). Methods: Patients were recruited from two Outpatient Movement Disorder Clinics (Ambulatório Bias Fortes, Universidade Federal de Minas Gerais, and Centro Metropolitano de Especialidades Médicas, Santa Casa de Belo Horizonte) between February and December 2019. Results: One hundred and eighty-five individuals answered a questionnaire with sociodemographic profiles, medical conditions, and the practice of PA and physical therapy. When comparing individuals from the two centers, differences were only observed concerning the frequency of comorbidities. Arterial hypertension proved to be the most prevalent comorbidity. Only 37.8% and 20.5% of the individuals reported practicing PA or physical therapy, respectively. Walking was the most common physical activity. Sedentary patients were older, had lower levels of education, presented a longer duration of PD, and were more affected by other comorbidities, when compared to more physically active patients. Conclusion: The present study shows the influence of age, education, and PD time on adherence to the practice of PA and physical therapy. Public health initiatives are needed to promote behavioral change and improve PA opportunities among individuals with PD
ABSTRACT
BACKGROUND: Neuroinflammation is an important part of stroke pathophysiology and has both detrimental and beneficial effects after stroke. Besides that the enhancement of neurotrophins seems to be related to improvements in stroke recovery. Evidences suggest that exercise plays a role in modulating anti-inflammatory and neurotrophic effects. However, little is known about its impact in stroke survivors, mainly in chronic stroke. The purpose of this study is to investigate the efficacy of moderate-intensity treadmill exercise in changing inflammatory mediators, interleukin-6 (IL-6), soluble tumor necrosis factor receptors I and II (sTNFRI, sTNFRII), interleukin-10 (IL-10), and brain-derived neurotrophic factor (BDNF) levels in chronic stroke patients. The secondary objective is to investigate the effects of training in improve mobility and exercise capacity. METHODS: This is a randomized controlled trial. Chronic stroke patients will be randomized to an experimental or control group, and will receive group interventions three times per week, over 12 weeks. The experimental group will receive moderate-intensity (60%-80% of maximum heart rate reserve) treadmill exercise. Control group will perform walking training on the ground (<40% of maximum heart rate reserve). Primary outcomes include IL-6, sTNFRI, sTNFRII, IL-10, and BDNF levels. Secondary outcomes include mobility and exercise capacity. Outcomes will be measured at baseline, postintervention, and at the 4-week follow-up. DISCUSSION: The findings of this trial have the potential to provide important insights regarding the effects of an aerobic physical program in the inflammatory process and in the neuronal plasticity in stroke persons and its impact on mobility and exercise capacity.
