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1.
Opt Lett ; 44(9): 2318-2321, 2019 May 01.
Article in English | MEDLINE | ID: mdl-31042213

ABSTRACT

Tunable femtosecond light sources in the short wave and middle wave infrared regions are of utmost importance for various applications ranging from multiphoton microscopy, mid-infrared supercontinuum generation to high-harmonic generation. We report on an all-fusion-spliced fiber laser emitting 80 fs pulses up to 2.9 µm with 35 kW peak power. The laser is based on Raman self-frequency shift effect from 1560 nm up to 3000 nm in germanium-doped fibers fabricated by the widespread modified chemical vapor deposition process.

2.
Opt Lett ; 43(20): 5098-5101, 2018 Oct 15.
Article in English | MEDLINE | ID: mdl-30320829

ABSTRACT

We introduce a fiber-based laser system providing 130 fs pulses with 3.5 nJ energy at 920 nm at a 43 MHz repetition rate and illustrate the potential of the source for two-photon excited fluorescence microscopy of living mouse brain. The laser source is based on frequency-doubling high-energy solitons generated and frequency-shifted to 1840 nm in large mode area fibers. This simple laser system could unleash the potential of two-photon microscopy techniques in the biology laboratory where green fluorescent proteins with two-photon absorption spectrum peaking around 920 nm are routinely used.

3.
Phys Rev Lett ; 117(23): 233902, 2016 Dec 02.
Article in English | MEDLINE | ID: mdl-27982619

ABSTRACT

The Astronomical Light Optical Hybrid Analysis project investigates the combined use of a telescope array interferometer and nonlinear optics to propose a new generation of instruments dedicated to high-resolution imaging for infrared astronomy. The nonlinear process of optical frequency conversion transfers the astronomical light to a shorter wavelength domain. Here, we report on the first fringes obtained on the sky with the prototype operated at 1.55 µm in the astronomical H band and implemented on the Center for High Angular Resolution Astronomy telescope array. This seminal result allows us to foresee a future extension to the challenging midinfrared spectral domain.

4.
Phys Rev Lett ; 112(14): 143904, 2014 Apr 11.
Article in English | MEDLINE | ID: mdl-24765966

ABSTRACT

In the field of high resolution imaging in astronomy, we experimentally demonstrate the spatial-coherence analysis of a blackbody using an up-conversion interferometer in the photon counting regime. The infrared radiation of the blackbody is converted to a visible one in both arms of the interferometer thanks to the sum-frequency generation processes achieved in Ti-diffused periodically poled lithium niobate waveguides. The coherence analysis is performed through a dedicated imaging stage which mimics a classical telescope array analyzing an astrophysical source. The validity of these measurements is confirmed by the comparison with spatial-coherence analysis through a reference interferometer working at infrared wavelengths.

5.
Acta Med Port ; 5(7): 373-8, 1992 Jul.
Article in Portuguese | MEDLINE | ID: mdl-1442182

ABSTRACT

Data from the population based Cancer Registry of Vila Nova de Gaia for the 1981-1987 period are presented. Cancer is becoming a disease increasingly frequent in Portugal, causing progressively higher mortality rates. Population and geographic characteristics of Vila Nova de Gaia country is presented. Information sources of this Registry are hospitals, pathology labs, Health Authority files and death certificates. Net (229.2, 216.6) and standardized for european population (369.9, 245.9) incidence rates are presented for respectively men and women. Comparisons with registries from other countries (e.s.) are made.


Subject(s)
Neoplasms/epidemiology , Adolescent , Adult , Aged , Child , Child, Preschool , Female , Humans , Incidence , Male , Middle Aged , Neoplasms/mortality , Portugal/epidemiology , Registries
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