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8.
Hipertensión (Madr., Ed. impr.) ; 19(2): 91-94, feb. 2002. ilus
Article in Es | IBECS | ID: ibc-11387

ABSTRACT

Se describe el caso de un paciente de 24 años de edad que desarrolló lesiones isquémicas en distintos órganos provocadas por la administración de radioterapia por un orquioblastoma en la infancia. Más de 20 años después de recibir irradiación con cobalto a altas dosis sobre la región abdominogenital presentó una pancreatitis crónica y una colangitis esclerosante, una nefropatía isquémica, con hipertensión arterial vasculorrenal secundaria a estenosis bilateral de arterias renales y un infarto isquémico del cono medular. De todas las lesiones, la que evolucionó más favorablemente fue la renal, ya que aunque la arteria renal derecha tenía una obstrucción prácticamente completa, la izquierda se consiguió dilatar mediante angioplastia transluminal percutánea, con buen resultado final y progresiva mejoría de la función renal. Sin embargo, fue necesario mantener la mayoría de los fármacos antihipertensivos, probablemente debido al efecto presor que seguía ejerciendo la arteria renal derecha ocluida. Tras más de dos años de seguimiento la función renal sigue siendo prácticamente normal y no existen datos de reestenosis de la arteria renal izquierda (AU)


Subject(s)
Adult , Male , Humans , Radiotherapy/adverse effects , Radiotherapy/methods , Hypertension, Renovascular/complications , Hypertension, Renovascular/diagnosis , Hypertension, Renovascular/radiotherapy , Kidney Diseases/complications , Kidney Diseases/diagnosis , Ischemia/complications , Angioplasty, Balloon/methods , Renal Artery Obstruction/diagnosis , Renal Artery Obstruction/radiotherapy , Peripheral Vascular Diseases/complications , Peripheral Vascular Diseases/diagnosis , Vascular Diseases/complications , Antihypertensive Agents/administration & dosage , Antihypertensive Agents/therapeutic use , Aortography/methods , Pancreatitis/complications , Cholangitis, Sclerosing/complications , Hypertension, Renovascular/therapy , Cobalt/therapeutic use
15.
Kidney Int Suppl ; 68: S73-7, 1998 Dec.
Article in English | MEDLINE | ID: mdl-9839288

ABSTRACT

The aging of Western societies is causing a progressive increase in the number of patients over 65 starting dialysis. The EDTA Registry shows that in 1995 this section of the population represented nearly 45% of patients under dialysis, and the percentage is even higher in the USRDS at 48%, 20% of whom are over 75. These changes have not only been quantitative, but have also modified the causes of end-stage renal disease (ESRD). Diabetic nephropathy (DN) and renal vascular disease (RVD) account for more than 50% of all these causes, reaching 66% according to the latest USRDS calculations. According to these numbers, RVD represents 29% of all causes, the incidence varying with the age group, and has become the main cause of ESRD in the elderly (38% of all cases). Until a few years ago, RVD was synonymous with hypertension, but as the population ages, the range of diseases in this group is increasing. The main RVDs that cause ESRD in the elderly are: hypertensive RVD (nephrosclerosis), atheromatous RVD (either as ischemic atherosclerotic nephropathy or as atheroembolism), and acute occlusion of renal arteries (either bilateral or unilateral in single-kidney patients). The diagnosis of nephrosclerosis in the absence of histological confirmation is a presumed clinical diagnosis, made in most cases by exclusion, and is therefore clearly overestimated. On the other hand, atheromatous RVD is an underdiagnosed disease that is often overlooked. The prevalence, natural history, diagnosis and prognosis are discussed in this report.


Subject(s)
Aging/physiology , Diabetic Nephropathies/epidemiology , Diabetic Nephropathies/physiopathology , Kidney/blood supply , Aged , Humans , Kidney/physiopathology , Registries/statistics & numerical data , Vascular Diseases/epidemiology , Vascular Diseases/physiopathology
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