ABSTRACT
Introduction: The use of medical Cannabis remains unregulated in several countries due to the scarcity of clinical studies with high scientific evidence that establish safety and efficacy of Cannabis products. This study aimed to comprehensively analyze how knowledge has been created in this field, as well as perform a bibliographic mapping to identify knowledge gaps, and investigate key authors and journals that have significantly contributed to advancing our understanding of Cannabis. Method: The study protocol was registered in the International Prospective Register of Systematic Review (CRD42020223084). A systematic search was conducted in the Cochrane Central Register of Controlled Trials, Lilacs, Google Scholar, PubMed, SciELO, Scopus, and Web of Science databases. The bibliographic analysis and mapping were registered using the VOSviewer, Sci2tool, CiteSpace, and PoP software. Results: The systematic search identified 27,597 records, with 17,020 duplicates, resulting in a total of 10,577 articles included. The authors who published the most were Marilyn Ann Huestis (n=108) and Sagnik Bhattacharyya (n=71), while Elisaldo A. Carlini and Raphael Mechoulam published 8 and 22 articles, respectively. The journals Drug and Alcohol Dependence (n=297), Psychopharmacology (n=159) and Addictive Behaviors (n=150) were the ones that published the most on Cannabis. The journals suggest that the articles are correlated with the adverse and toxicological effects of recreational Cannabis use; however, most articles focus on medical Cannabis. The peak of publications was in 2021 (n=1,481). The countries that published the most were the United States (n=9,735), while Brazil occupied the 11th position (n=422). Most publications were carried out in "Pharmacology and Pharmacy" (11.31%), followed by "Psychiatry" (7.66%) and "Medicine" (5.80%). The areas of "Neurosciences" (1.59%), "Biochemistry," "Genetics," and "Molecular Biology" (0.79%) were little explored. Conclusion: This study captured the characteristics of publications about Cannabis and clinical studies in the scientific literature, yielding >10,000 articles, representing a large literature review, to date. Therefore, the most productive countries included the United States, the United Kingdom, and Canada, while the most productive authors were Marilyn Ann Huestis and Sagnik Bhattacharyya, with a peak of publications in 2021. Finally, the most chosen journals were Drug and Alcohol Dependence and Psychopharmacology.
Subject(s)
Alcoholism , Cannabis , Medical Marijuana , United States , Medical Marijuana/therapeutic use , Bibliometrics , PubMed , Cannabinoid Receptor AgonistsABSTRACT
Objetivo:Avaliar o perfil epidemiológico e a qualidade de vida das pessoas idosas com estomias de eliminação de uma microrregião de saúde de Minas Gerais. Métodos: Trata-se de um estudo transversal realizado em um serviço público de atenção à saúde. Para descrição do perfil foram avaliados todos os prontuários de pessoas idosas com estomias. Em seguida, foi avaliada a qualidade de vida por meio do questionário City of Hope-Quality of Life-Ostomy Questionnaire. Resultados: Verificou-se uma população majoritariamente feminina (55,2%) com idade média de 67 anos (± 8,8). As estomias eram em 64% definitivas, tendo o câncer colorretal o principal diagnóstico (71%) e em 41,4% apresentavam dependência parcial para o autocuidado. Com relação à avaliação da qualidade de vida, os domínios bem-estar espiritual, físico e social apresentaram melhores indicadores de avaliação (8,1; 8,1; e 8,2 respectivamente). Evidenciou-se que o tipo de estomia e o tempo de permanência se associam negativamente com a qualidade de vida das pessoas com estomias. Conclusão: A qualidade de vida de idosos com estomia de eliminação mostrou-se bem avaliada, principalmente nos domínios bem-estar físico, social e espiritual.
Objective:The aim of this study was to assess the epidemiological profile and quality of life of elderly people with elimination ostomy in a health region in Minas Gerais. Methods: This is a cross-sectional study carried out in a public health care service. To describe the profile, all medical records of elderly people with ostomy were evaluated. Then, quality of life was assessed using the City of Hope-Quality of Life-Ostomy Questionnaire. Results:There was a mostly female population (55.2%) with a mean age of 67 years (± 8.8). In 64%, the ostomies were definitive, with colorectal cancer being the main diagnosis (71%) and in 41.4% they were partially dependent on self-care. Regarding the assessment of quality of life, the domains of spiritual, physical and social well-being had better assessment indicators (8.1; 8.1; and 8.2 respectively). It was evident that the type of ostomy and the length of stay are negatively associated with the quality of life of people with ostomies. Conclusion: The quality of life of elderly people with an elimination ostomy was well evaluated, especially in the domains of physical, social and spiritual well-being.
Objetivo:El objetivo de este estudio fue evaluación del perfil epidemiológico y la calidad de vida de los ancianos con ostomía en una región sanitaria de Minas Gerais. Métodos: Se trata de un estudio transversal realizado en un servicio público de salud. Para describir el perfil se evaluaron todas las historias clínicas de ancianos con ostomía. Luego, la calidad de vida se evaluó mediante el Cuestionario City of Hope-Quality of Life-Ostomy. Resultados: Se encontró una población mayoritariamente femenina (55,2%) con una edad media de 67 años (± 8,8). En el 64% las ostomías fueron definitivas, siendo el cáncer colorrectal el diagnóstico principal (71%) y en el 41,4% fueron parcialmente dependientes del autocuidado. En cuanto a la evaluación de la calidad de vida, los dominios de bienestar espiritual, físico y social presentó mejores indicadores de evaluación (8.1; 8.1; y 8.2 respectivamente). Se evidenció que el tipo de ostomía y la duración de la estancia se asocian negativamente con la calidad de vida de las personas con ostomías. Conclusión: La calidad de vida de los ancianos con ostomía de eliminación fue bien evaluada, especialmente en los dominios de bienestar físico, social y espiritual.
