ABSTRACT
The clinical, neuropsychological and computed tomography data were compared in elderly and senile patients with trembling and akinetico-rigid forms of parkinsonism. 12 patients with trembling and 21 with akinetico-rigid forms were examined. The groups did not differ in age or sex. The results of computed brain tomography were estimated with the use of linear, volumetric and densitometric parameters. The akinetico-rigid form was associated with more diverse clinical and neuropsychological symptomatology, more noticeable cerebral atrophy. The gravity of the status of the patients with trembling parkinsonism was largely specified by the intensity of the hyperkinetic syndrome whereas that of the patients with the akinetico-rigid form not only by amyostatic disorders but also by the presence and severity of discoordination, pseudobulbar and mnemonic-intellectual disturbances. Disorders revealed in the patients with the akinetico-rigid form often attest to the dysfunction of the frontal parts of the brain. The nosological heterogeneity of these two forms of parkinsonism is under discussion.
Subject(s)
Cognition Disorders/diagnosis , Muscle Rigidity/diagnosis , Neurocognitive Disorders/diagnosis , Parkinson Disease/diagnosis , Tremor/diagnosis , Age Factors , Aged , Brain/diagnostic imaging , Cognition Disorders/etiology , Echoencephalography , Female , Humans , Male , Middle Aged , Muscle Rigidity/etiology , Neurocognitive Disorders/etiology , Parkinson Disease/classification , Parkinson Disease/complications , Parkinson Disease/psychology , Tomography, X-Ray Computed , Tremor/etiologyABSTRACT
The clinical, neuropsychological and computer-aided tomography data were compared in elderly and senile patients suffering from trembling and akinetic rigid forms of parkinsonism. 12 patients with trembling and 21 with akinetic rigid parkinsonism were examined. The groups did not differ in age or sex. The results of computer-aided tomography of the brain were evaluated using linear, volumetric and densitometric parameters. The akinetic rigid pattern was found to be associated with a more diverse clinical and neuropsychological symptomatology, by more manifest cerebral atrophy. The gravity of the status of patients with trembling parkinsonism is largely determined by the intensity of the hyperkinetic syndrome, that of patients with akinetic rigid parkinsonism not only by amyostatic disturbances but also by the presence and severity of incoordination , pseudobulbar and mnemonic intellectual disorders. The disorders identified in patients with akinetic rigid parkinsonism often attest to dysfunction of the frontal parts of the brain. The nosological heterogeneity of both patterns of parkinsonism is assumed.
Subject(s)
Brain/diagnostic imaging , Cognition Disorders/diagnosis , Muscle Rigidity/diagnosis , Neurocognitive Disorders/diagnosis , Parkinson Disease/diagnosis , Tremor/diagnosis , Age Factors , Aged , Cerebral Ventriculography , Cognition Disorders/etiology , Echoencephalography , Electroencephalography , Female , Humans , Male , Middle Aged , Muscle Rigidity/etiology , Neurocognitive Disorders/etiology , Neuropsychological Tests , Parkinson Disease/classification , Parkinson Disease/complications , Parkinson Disease/psychology , Tomography, X-Ray Computed , Tremor/etiologySubject(s)
Brain Diseases/pathology , Brain/pathology , Aged , Aged, 80 and over , Atrophy/physiopathology , Brain/diagnostic imaging , Brain/physiopathology , Brain Diseases/diagnostic imaging , Brain Diseases/physiopathology , Dementia/physiopathology , Female , Hearing Disorders/diagnostic imaging , Hearing Disorders/physiopathology , Humans , Male , Memory Disorders/diagnostic imaging , Memory Disorders/pathology , Memory Disorders/physiopathology , Middle Aged , Psychomotor Performance/physiology , Speech/physiology , Tomography, X-Ray ComputedABSTRACT
Altogether 55 patients of the elderly and senile age with chronic cerebrovascular insufficiency underwent neuropsychological examinations according to A. R. Luria's techniques. Based on the volumetric CT-parameters the patients were distributed into 4 groups: with minimum atrophic alterations, external, internal and mixed types of cerebral atrophy (CA). The most pronounced disorders of higher cerebral functions were revealed in patients with the internal and mixed types of CA. The characteristic feature of the neuropsychological disorders in the examined patients with dementia was the domination of the signs of frontal brain dysfunction. The data obtained attest to the leading part of the pathology of profound structures of the brain and their relations to the frontal parts in the genesis of the neurological and neuropsychological disorders in elderly and senile patients with chronic cerebrovascular insufficiency.
