[Mechanism of early metabolism disorders and immunological reactivity in children with Perthes disease]. / O mekhanizme rannikh narushenii obmena i immunologicheskoi reaktivnosti u detei s bolezn'iu Pertesa.

Submitted in the paper are data to the effect that parameters of certain biochemical indices for blood plasma and cell link of the immune system could allow some judgement about the character of the pathological process in children with Perthes disease. Autoimmune inflammation caused by foci of chronic infection in the organism aggravates the course of aseptic necrosis in the proximal portion of the thighbone or else is a trigger mechanism of its development.

[Diagnostic significance of certain cellular immune system disorders in children with Perthes disease]. / Diagnosticheskoe znechenie nekotorykh narushenii kletochnogo zvena immunnoi sistemu u detei s bolezn'iu Pertesa.

Data are submitted to the effect that parameters associated with the cell link of the immune system should allow some judgement about character and degree of time-related immunological abnormalities in children with Perthes disease. In the earliest stages of the illness immunological abnormalities are in large measure related to the presence of foci of chronic bacterial infection as evidenced by a high NBT-test. The above immunological abnormalities aggravate the course of aseptic necrosis of the hip joint or they serve as a trigger mechanism of its development.