ABSTRACT
This paper provides a rationale for, and overview of, procedures used to develop the National Latino and Asian American Study (NLAAS). The NLAAS is nationally representative community household survey that estimates the prevalence of mental disorders and rates of mental health service utilization by Latinos and Asian Americans in the US. The central aims of the NLAAS are to: 1) describe the lifetime and 12-month prevalence of psychiatric disorders and the rates of mental health services use for Latino and Asian American populations using nationwide representative samples of Latinos and Asian Americans, 2) assess the associations among social position, environmental context, and psychosocial factors with the prevalence of psychiatric disorders and utilization rates of mental health services, and 3) compare the lifetime and 12-month prevalence of psychiatric disorders, and utilization of mental health services of Latinos and Asian Americans with national representative samples of non-Latino whites (from the National Comorbidity Study-Replication) (NCS-R) and African Americans (from the National Survey of American Life) (NSAL). This paper presents new concepts and methods utilized in the development of the NLAAS to capture and investigate ethnic, cultural and environmental considerations that are often ignored in mental health research.
Subject(s)
Asian/psychology , Cross-Cultural Comparison , Hispanic or Latino/psychology , Mental Disorders/ethnology , Social Environment , Adolescent , Adult , Aged , Asian/statistics & numerical data , Bayes Theorem , Cultural Diversity , Emigration and Immigration/statistics & numerical data , Female , Health Surveys , Hispanic or Latino/statistics & numerical data , Humans , Male , Mental Disorders/diagnosis , Mental Disorders/epidemiology , Mental Health Services/statistics & numerical data , Middle Aged , United States/epidemiology , Utilization Review/statistics & numerical dataABSTRACT
The 2.6 kb fragment which can complement the Exo(-)Ndv(-)Fix(-) mutants of R. huakuii to Exo(+)Nod(+)Fix(+) was sequenced. The result revealed the presence of an open reading frame exo1, which encodes 340 amino acids. Analysis of the hydrophobicity plot of the putative protein indicated that it was a cytoplasmic protein. Exo1 displayed strong homology to the ExoU protein of R. meliloti, which was a glucosyltransferase. A transcriptional fusion to lacZ using the promoterless vector pMP221 showed that there were two regions with promoter activity in exo1. Pexo1a was identified upstream of exo1, and Pexo1b in the middle of exo1. Pexo1a probably contains the promoter of exo1 gene.
