Analysis of primary nursing intervention for elderly patients with cancer pain on the improvement of potential risk and pain degree.

OBJECTIVE: To analyze the effect of primary nursing on the improvement of potential risk and pain degree in elderly patients with cancer pain. METHODS: Altogether 187 patients with cancer pain from June 2018 to November 2019 were selected as the research participants and grouped into two groups according to different nursing intervention methods, including 102 cases in the research group (RG) and 85 cases in the control group (CG). The pain relief and medication compliance were evaluated. General Self-efficacy Scale (GSES) and Exercise of Self-Care Agency (ESCA) were used to evaluate the self-efficacy and self-care ability. Self-rating Anxiety Scale (SAS) and Self-rating Depression Scale (SDS) were used to evaluate the anxiety and depression. Pittsburgh Sleep Quality Index (PSQI) was used to evaluate sleep quality. SF-36 Quality of Life Scale was used to evaluate the quality of life. Self-made nursing satisfaction questionnaire was used to evaluate the nursing satisfaction. RESULTS: The improvement of pain relief in the RG was evidently higher than that in the CG. The scores of SAS and SDS in the RG after intervention were evidently lower than those in the CG. GSES and ESCA scores of patients in the RG after intervention were evidently higher than those in the CG. The compliance of patients in the RG after intervention was evidently higher than that in the CG. The PSQI scores of patients in the RG after intervention were evidently better than those in the CG. The scores of SF-36 and nursing satisfaction in the RG were evidently higher than those in the CG. CONCLUSION: The implementation of primary nursing intervention for elderly patients with cancer pain can effectively relieve their pain and improve their bad psychological state and medication compliance, thus improving patients' quality of life.

Organometallic complexes in supported ionic-liquid phase (SILP) catalysts: a PHIP NMR spectroscopy study.

para-Hydrogen induced polarization (PHIP) NMR spectroscopy emerges as an efficient and robust method for on-line monitoring of gas-phase hydrogenation reactions. Here we report detailed investigations of supported ionic liquid phase (SILP) catalysts in a continuous gas-phase hydrogenation of propene with PHIP NMR spectroscopy. A relocation of the rhodium complex in the thin layer of ionic liquid in the SILP catalyst at the initial stage of the propene hydrogenation is demonstrated. PHIP NMR spectroscopy can provide profound insight into the evolution of SILP catalysts during hydrogenation reactions.

Trace analysis by low-field NMR: breaking the sensitivity limit.

Sensitivity poses a persistent challenge to NMR spectroscopy and magnetic resonance imaging (MRI). Nonhydrogenative para-hydrogen induced polarization (NH-PHIP) has recently emerged as an efficient method to substantially increase the sensitivity of high-field NMR. Here, we report the feasibility of applying NH-PHIP in the low-field NMR. A trace amount of pyridine of just a few nanoliters ( approximately 12 nmol) in a 0.4 mL NMR sample (a concentration of 31 microM or 10(16)/cm(3)) could be measured in a single scan by NH-PHIP. There is a striking difference in the signal-to-noise ratio (SNR) between thermal prepolarization and NH-PHIP: The SNR of the prepolarized (1)H NMR signal decreases linearly with decreasing (1)H concentration ([(1)H]) while the SNR in NH-PHIP experiments first increases with decreasing [(1)H], then remains constant over 2 orders of magnitude, and finally decreases linearly with decreasing [(1)H]. A hitherto unknown potential opens up for trace analysis by low-field NMR in the bio-, chemical, and material sciences.

NMR relaxation and self-diffusion study at high and low magnetic fields of ionic association in protic ionic liquids.

NMR relaxation and diffusion characterization of several protic ionic liquids at high and low magnetic fields are reported. The dynamics of cations and anions were similar at both frequencies, with similar trends and magnitudes for a fixed component paired with oppositely charged species. An Arrhenius relationship was displayed between the molecular motion and the glass transition temperature. The diffusion of ions showed a strong degree of ion correlation between cation and anion, and Arrhenius plots of relaxation and diffusion indicated that the ions diffused as a pair. At high field diffusion was dominated by mobile species that followed Stokes-Einstein behavior. Conversely, diffusion observed at low field emphasized relatively immobile species that displayed fractional Stokes-Einstein behavior. No evidence was found to indicate the influence of magnetic field on structural and dynamic properties of the studied ILs; however, variation between diffusion coefficients at different magnetic fields indicated dynamic heterogeneities (or temporal aggregates) within the ionic liquid.

NMR with excitation modulated by Frank sequences.

Miniaturized NMR is of growing importance in bio-, chemical, and -material sciences. Other than the magnet, bulky components are the radio-frequency power amplifier and the power supply or battery pack. We show that constant flip-angle excitation with phase modulation following a particular type of polyphase perfect sequences results in low peak excitation power at high response peak power. It has ideal power distribution in both the time domain and the frequency domain. A savings in peak excitation power of six orders of magnitude has been realized compared to conventionally pulsed excitation. Among others, the excitation promises to be of use for button-cell operated miniature NMR devices as well as for complying with specific-absorption-rate regulations in high-field medical imaging.