ABSTRACT
It was investigated the influence of a diet supplemented with amaranth oil on dynamic of lipid profile and composition of fatty acids of erythrocytes in patients with ischemic heart disease and hyperlipoproteidemia. The efficacy of diet with different contents of squalene (100, 200, 400 and 600 mg per day) was compared. It was shown that antiatherosclerotic diet with including 600 mg squalene has promoted the most positive changes of the serum cholesterol and triglycerides level and fatty acid composition of erythrocytes membranes as well.
Subject(s)
Amaranthus , Hyperlipoproteinemias/blood , Lipid Metabolism/drug effects , Myocardial Ischemia/blood , Phytotherapy , Plant Oils/therapeutic use , Amaranthus/chemistry , Cholesterol/blood , Fatty Acids/blood , Female , Humans , Hyperlipoproteinemias/diet therapy , Male , Myocardial Ischemia/diet therapy , Plant Oils/administration & dosage , Plant Oils/chemistry , Squalene/administration & dosage , Squalene/therapeutic use , Triglycerides/bloodABSTRACT
In experiment on rats it was shown a hypocholesterolemic effect of amaranth oil. The decrease of cholesterol lever in rat blood was not accompanied by its increasing in a liver. The turn from a model of hypercholesterolemia to the diet with amaranth oil also prodused decreasing of cholesterol lever in rat plasma and liver as compared with control animals. In the composition of rat liver sterins the increasing of plant sterins was observed that probably was due to squalene presense in amaranth oil.
Subject(s)
Amaranthus , Diet , Hypercholesterolemia/blood , Lipid Metabolism/drug effects , Plant Oils/administration & dosage , Amaranthus/chemistry , Animals , Cholesterol/blood , Disease Models, Animal , Hypercholesterolemia/diet therapy , Liver/metabolism , Male , Plant Oils/chemistry , Rats , Rats, Wistar , Squalene/administration & dosage , Squalene/chemistryABSTRACT
It was investigated the influence of a diet supplemented with amaranth oil on dynamic of antioxidant and immune status in 125 patients with ischemic heart disease and hyper-lipoproteidemia. The efficacy of diets with different contents of squalene (100, 200, 400, 600 mg per day) was compared. It was shown that antiatherosclerotic diet with inclusion 600 mg squalene has promoted the most positive changes of immune status. The consumption of 200-400 mg of squalene per day produced the more significant antioxidant effect.
Subject(s)
Amaranthus , Dietary Supplements , Hyperlipoproteinemias/diet therapy , Myocardial Ischemia/diet therapy , Safflower Oil/administration & dosage , Squalene/administration & dosage , Administration, Oral , Adult , Aged , Amaranthus/chemistry , Amaranthus/immunology , Antioxidants/analysis , Dose-Response Relationship, Drug , Female , Humans , Hyperlipoproteinemias/blood , Hyperlipoproteinemias/immunology , Immunoglobulin G/blood , Immunoglobulin G/immunology , Immunoglobulin M/blood , Immunoglobulin M/immunology , Lipid Peroxidation/drug effects , Male , Middle Aged , Myocardial Ischemia/blood , Myocardial Ischemia/immunologyABSTRACT
Investigation of influence of an antisclerotic diet with a probiotical sour-milk product enriched with an extract of leaves of an amaranth in patients with ishemic heart disease and hypertension was conducted. As a result of a diet were positive dynamic of clinic manifestation, lipid spectrum of blood, coagulogramms and antioxigen status.
