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[Single-dose toxicological test for leptospirosis vaccine vax-SPIRAL in mice]. / Prueba toxicológica de dosis única para la vacuna antileptospirósica vax-sPIRAL en ratones.
Bourzac, Juan Francisco Infante; Rodríguez, Sergio Sifontes; González, Martha González; Amat, Viviana Pérez; Medina, Mildrey Fariñas.
Rev Cubana Med Trop ; 57(1): 65-6, 2005.
Article in Spanish | MEDLINE | ID: mdl-17966486

ABSTRACT

The single-dose toxicological test for the leptospirosis vaccine vax-SPIRAL was made in rats. No clinical toxicity symptoms were found. The differences between the evaluated variables were not important from the biological point of view.


Subject(s)
Bacterial Vaccines/toxicity , Leptospira interrogans/immunology , Leptospirosis/prevention & control , Toxicity Tests , Animals , Bacterial Vaccines/administration & dosage , Disease Models, Animal , Female , Male , Mice , Time Factors
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