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Muscle Nerve ; 59(5): 555-560, 2019 05.
Article in English | MEDLINE | ID: mdl-30697788

ABSTRACT

INTRODUCTION: Short tau inversion recovery (STIR) sequences in whole-body MRI are usually used for detecting muscle edema (ME) in inflammatory myopathies. We evaluated b-value 800 diffusion-weighted imaging (b800 DWI). METHODS: Two radiologists independently and a consensus reader retrospectively reexamined 60 patients with inflammatory myopathies and 15 controls. For each participant, 78 muscles were analyzed with 3 sets of imaging acquisitions: T1-weighted (T1) turbo spin echo and STIR; T1 and DWI; and T1, STIR and DWI. Mean edema per patient was compared between sequences. Agreement was evaluated. RESULTS: Diffusion-weighted imaging detected more ME compared with STIR (P < 0.001). Agreement between readers was better with both sequences (k = 0.94) than with b800 DWI (k = 0.89) or STIR (k = 0.84) alone. DISCUSSION: Diffusion-weighted imaging is a valuable add-on for the study of inflammatory myopathies. Muscle Nerve 59:555-555, 2019.


Subject(s)
Edema/diagnostic imaging , Muscle, Skeletal/diagnostic imaging , Myositis/diagnostic imaging , Adolescent , Adult , Aged , Aged, 80 and over , Case-Control Studies , Creatine Kinase/blood , Dermatomyositis/blood , Dermatomyositis/diagnostic imaging , Dermatomyositis/pathology , Diffusion Magnetic Resonance Imaging , Female , Fructose-Bisphosphate Aldolase/blood , Humans , Male , Middle Aged , Muscle, Skeletal/pathology , Myositis/blood , Myositis/pathology , Myositis, Inclusion Body/blood , Myositis, Inclusion Body/diagnostic imaging , Myositis, Inclusion Body/pathology , Polymyositis/blood , Polymyositis/diagnostic imaging , Polymyositis/pathology , Retrospective Studies , Whole Body Imaging , Young Adult
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