ABSTRACT
Objetivos: Mostrar el valor de la resonancia magnética (RM) en el diagnóstico de la enfermedad de Creutzfeldt-Jakob (ACJ) y familiarizar al radiólogo con los hallazgos característicos de esta entidad. Material y métodos: Se realizó un estudio retrospectivo de 6 pacientes diagnosticados de ACJ en nuestro centro en el período 20042008. Se revisaron los datos clínicos, analíticos, electroencefalográficos y los hallazgos radiológicos de cada caso y se correlacionaron con los resultados de la necropsia o con los criterios de la Organización Mundial de la Salud (OMS) de ACJ en los casos en los que no se disponía del examen histopatológico. Resultados: De los 6 pacientes diagnosticados de ACJ, 4 tienen necropsia que confirma la enfermedad y en 2 no se dispone de ésta. Éstos cumplen los criterios de la OMS de ACJ, uno probable y otro posible. Resultados: En todos los casos observamos que en los estudios de RM aparecían alteraciones características de la enfermedad a nivel cortical y/o de ganglios basales. Estas alteraciones se detectaron en fases clínicas iniciales. Conclusiones: En la ACJ, la RM muestra alteraciones características que deben conocerse para poder realizar un diagnóstico precoz (AU)
Objectives: To show the usefulness of magnetic resonance imaging in the diagnosis of Creutzfeldt-Jakob disease (CDJ) and to familiarize the radiologist with the characteristic imaging findings for this entity. Results: In all cases, we observed characteristic alterations on magnetic resonance imaging at the level of the cortex and/or basal ganglia. These alterations were detected in the initial clinical phases. Conclusions: Radiologists should be familiar with the characteristic alterations of CDJ at magnetic resonance imaging to enable the early diagnosis of this entity (AU)
Subject(s)
Humans , Male , Female , Middle Aged , Aged , Aged, 80 and over , Creutzfeldt-Jakob Syndrome , Magnetic Resonance Imaging , Magnetic Resonance Spectroscopy/methods , Dementia/complications , Dementia/diagnosis , Creutzfeldt-Jakob Syndrome/diagnosis , Creutzfeldt-Jakob Syndrome , Retrospective Studies , Early Diagnosis , Dementia , Electroencephalography , Brain/physiopathology , BrainABSTRACT
OBJECTIVES: To show the usefulness of magnetic resonance imaging in the diagnosis of Creutzfeldt-Jakob disease (CDJ) and to familiarize the radiologist with the characteristic imaging findings for this entity. MATERIAL AND METHODS: We retrospectively studied six patients diagnosed with Creutzfeldt-Jakob disease at our center from 2004 through 2008. We reviewed the clinical, laboratory, electroencephalographic, and imaging findings in each case, and we correlated the results with the autopsy findings or with the World Health Organization's criteria for CDJ in the cases for which histopathological data were not available. RESULTS: Of the six patients diagnosed with CDJ, autopsy findings confirming the diagnosis were available in four patients and the other two patients fulfilled the World Health Organization's criteria for the diagnosis (one classified as probable and other as possible). In all cases, we observed characteristic alterations on magnetic resonance imaging at the level of the cortex and/or basal ganglia. These alterations were detected in the initial clinical phases. CONCLUSIONS: Radiologists should be familiar with the characteristic alterations of CDJ at magnetic resonance imaging to enable the early diagnosis of this entity.
Subject(s)
Creutzfeldt-Jakob Syndrome/diagnosis , Magnetic Resonance Imaging , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Retrospective StudiesABSTRACT
El trastorno delirante crónico (TDC) se caracteriza por la presencia de ideas delirantes no extrañas, sin alucinaciones ni alteraciones del lenguaje o el pensamiento y que no conllevan deterioro de la personalidad
Chronic delusional disorder (CDD) is characterized by the presence of non-rare delusional ideas, without hallucinations or speech or thought disorders and does not entail personality deterioration
Subject(s)
Male , Female , Middle Aged , Aged , Humans , Schizophrenia, Paranoid/diagnosis , Schizophrenia, Paranoid/drug therapy , Antipsychotic Agents/therapeutic use , Diagnostic and Statistical Manual of Mental DisordersABSTRACT
No disponible
Subject(s)
Adult , Male , Humans , Tuberculosis, Pulmonary , Antitubercular Agents , Treatment Outcome , Radiography, Thoracic , Pleural Effusion , Mycobacterium tuberculosisSubject(s)
Pleural Effusion/microbiology , Tuberculosis, Pulmonary/complications , Adult , Antitubercular Agents/therapeutic use , Humans , Male , Mycobacterium tuberculosis/isolation & purification , Pleural Effusion/diagnostic imaging , Pleural Effusion/drug therapy , Radiography, Thoracic , Treatment Outcome , Tuberculosis, Pulmonary/diagnostic imaging , Tuberculosis, Pulmonary/drug therapyABSTRACT
We present the results of the registry of patients of the Cuban Commission of Cystic Fibrosis up to December, 1977. 228 patients from 192 families are reported; 81.58% were Whites and 3% were Negroes. There was no sex difference in incidence. Respiratory manifestations at diagnosis were presnet in 93% of the C.F. patients. The initial Shwachman's score were of "severe" or "moderate" in one third of the patients to whom they were made. Our Commission has followed 205 patients, one third of them died and out of the rest, we consider that 64% has a good outlook; approximately 10% has poor outlook and 26% has an uncertain prognosis. All this having in mind that the Shwachman's score, in a broad sense, has been useful to establish the prognosis. The most frequent findings in the dead pateints to whom autopsies were performed were in the lungs, the pancreas and the liver. It was observed that the lower the initial score, the lower the survival.
