[Adrenal hemangioma of atypical presentation. Bibliographical Review]. / Hemangioma adrenal de presentación atípica. Revisión bibliográfica.

OBJECTIVE: To report a case of adrenal hemangioma presenting as spontaneous massive retroperitoneal hemorrhage that required surgical treatment without preoperative hormonal study. METHODS/RESULTS: Due to the intense pain and hemodynamic instability, the patient described herein was immediately submitted to laparatomy, adrenalectomy and drainage. The literature is reviewed with special reference to the clinical and radiological findings that could permit making a correct preoperative diagnosis. To our knowledge, a similar form of presentation has not been reported in the literature. The patient is asymptomatic 8 months postoperatively. CONCLUSIONS: Adrenal hemangioma is a rare tumor that usually presents as an incidental finding or with chronic pain in the abdominal flank. Although it is rarely malignant and some authors advocate conservative management based on the radiological findings, the difficulty lies in the similar evolution of other adrenal tumors that can produce similar findings. We therefore advocate surgical excision of adrenal incidentalomas due to their indeterminate histological and clinical behaviour.

[Evaluation of an ultramicroELISA system for the diagnosis of rubella]. / Evaluación de un sistema ultramicroELISA para el diagnóstico de la rubéola.

An indirect Ultramicro ELISA assay, previously standardized in our laboratory, for detecting antibodies IgG to the rubella virus was assessed in comparison to the hemagglutination inhibition technique. This assessment allowed to determine its efficacy in the National System for Epidemiological Surveillance of this entity. One hundred and ninety serum pairs of clinically suspected cases of rubella were studied and a high percent of coincidence (99.4%), specificity (99.4%), and sensitivity (100%) was found between both techniques. In addition, 73 serum samples of blood donors were processed using an indirect microELISA system (Berhing) which was compared to the Ultramicro ELISA technique for rubella and it showed a 100% of sensitivity, specificity, and coincidence.

[Applying an ultramicroanalytical system to the diagnosis of infectious diseases]. / Algunas aplicaciones del sistema ultramicroanalítico al diagnóstico de enfermedades infecciosas.

The multiple applications and advantages of the ultramicro analytical system in the serodiagnosis of different diseases produced by viruses, bacteria, and parasites are briefly reported. Also, perspectives in the use of this technology, not only for the diagnosis, but for the detection of microbial antigens are pointed out.