ABSTRACT
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Subject(s)
Humans , Female , Adult , Erythema/diagnosis , Angiofibroma/diagnosis , Collagen Diseases/pathology , Biopsy , Skin Neoplasms/pathologySubject(s)
Angiofibroma/diagnosis , Collagen Diseases/diagnosis , Neoplastic Syndromes, Hereditary/diagnosis , Proto-Oncogene Proteins/genetics , Skin Neoplasms/diagnosis , Adult , Angiofibroma/genetics , Angiofibroma/pathology , Biopsy , Collagen Diseases/genetics , Collagen Diseases/pathology , Erythema/etiology , Facial Dermatoses/etiology , Facial Neoplasms/genetics , Facial Neoplasms/pathology , Female , Genes, Dominant , Humans , Hyperparathyroidism, Primary/blood , Hyperparathyroidism, Primary/genetics , Neoplastic Syndromes, Hereditary/genetics , Neoplastic Syndromes, Hereditary/pathology , Parathyroid Hormone/blood , Skin Neoplasms/genetics , Skin Neoplasms/pathology , TorsoABSTRACT
95 pleural effusions of different etiology were studied. 25 were transudate, 22 neoplastic, 28 caused by tuberculosis, and 20 miscellaneous. The Light parameters (pleural protein/plasma) (Prot LP/P), Pleural LDH (LDH LP) and LDH pleural/plasma quotient (LDH LP/P) were determined and compared with the efficacy of pleural cholesterol (Chol LP) and pleural cholesterol/plasma quotient (Chol LP/P) to differentiate the transudate from pleural exudate. With Prot LP/P quotient the sensitivity was of 85% and the specificity 91.6%; with LDH LP the sensitivity was of 74.6% and the specificity 97.6%. With the LDH LP/P quotient the sensitivity was of 89% and the specificity 87.8%. The sensitivity of each parameter was similar to that obtained by Light but less specific. All the transudates had levels of chol LP lower than 55 mq/dl (100% specificity) with a sensitivity of 84%. The Chol LP/P quotient had a limit of 0.3, this being its sensitivity of 91.3% and 93.1% its specificity. The presence of both parameters were necessary to the classification and the sensitivity obtained being of 80.3% and the specificity 100%. We concluded that the determinations of Chol LP and the Chol LP/P quotient are of great advantage in differentiating the pleural transudate from pleural exudate and the predictive value is, at least, similar to that obtained by Light.
