ABSTRACT
The current knowledge status on the patogenesis of endometriosis as well as devastating consequences of disease evolution in women's reproductive health, have promoted researchers advances in a great manner during last years. The immunologic and neangiogenesis systems implication have opened new ways of knowledge over classic theories from the beginning of the xx century. The experimental resesearch, using animal induction models. Below we explain the first steps a new induction model ("PGR1-HotDog"), based on Wistar rats using a new disease autogeneration system, created for te study of the early stages of the endometriosis.
Subject(s)
Disease Models, Animal , Endometriosis , Animals , Female , Microsurgery , Rats , Rats, WistarABSTRACT
El desconocimiento actual sobre la patogenia de la endometriosis ylas devastadores consecuencias que conlleva esta enfermedad paralas mujeres en edad reproductiva, han sido las grandes promotorasde los esfuerzos de los investigadores en los últimos años. La implicaciónpatogénica del sistema inmunológico, así como de los procesosneoangiogénicos ha abierto una gran vía de conocimiento sobre lasteorías clásicas conocidas desde principios del siglo XX. Todo ello, pasapor la investigación experimental de la endometriosis, en modelosanimales, con sistemas de inducción de la enfermedad. A continuaciónexplicamos los primeros resultados de un nuevo modelo experimentalde autogeneración de endometriosis en rata Wistar (PGR1-HotDog),creado con una fi nalidad, el conocimiento de las fases más precocesde la enfermedad (AU)
The current knowledge status on the patogenesis of endometriosis aswell as devastating consequences of disease evolution in women´sreproductive health, have promoted researchers advances in a greatmanner during last years. The immunologic and neangiogenesis systemsimplication have opened new ways of knowledge over classic theoriesfrom the beginning of the XX century. The experimental resesearch,using animal induction models. Below we explain the fi rst steps a newinduction model (PGR1-HotDog), based on Wistar rats using a newdisease autogeneration system, created for te study of the early stagesof the endometriosis (AU)
Subject(s)
Humans , Female , Endometriosis/surgery , Microsurgery , Disease Models, Animal , Rats, WistarABSTRACT
No disponible
Subject(s)
Female , Adolescent , Humans , Teratoma/pathology , Ovarian Neoplasms/pathologyABSTRACT
204 cases of invasive carcinoma of the uterine cervix seen in the period 1972-1985 are studied. The incidence was higher from 50 to 69 years of age and maximum during the last years of the decade of the fifties. It was verified that the early beginning of sexual intercourse increases the number of cases and the age of presentation, and also that invasive uterine cervix cancer is more common in women with 3 or more pregnancies, while the incidence decreases in women with 1 or 2 pregnancies and specially in nulliparous virgins.
Subject(s)
Uterine Cervical Neoplasms/epidemiology , Aged , Female , Humans , Middle Aged , Neoplasm Invasiveness , Parity , SpainABSTRACT
The combined use of colposcopy and cytology allows the diagnosis of 98.39 per cent of the cases of invasive cervical carcinoma.
Subject(s)
Uterine Cervical Neoplasms/pathology , Colposcopy , Female , Humans , Neoplasm Invasiveness , Vaginal SmearsABSTRACT
CIN I and CIN II can be treated by colposcopy-guided biopsy. Control examinations must be made every six months. Persistence of a CIN II lesion is an indication for conization. Some CIN III cases can be treated by conization, but considering the frequency of residual lesions and insufficient conization, a total hysterectomy is a safer procedure.
