ABSTRACT
No disponible
Subject(s)
Humans , Female , Aged , Neoplasm Metastasis/diagnosis , Skin Neoplasms/secondary , Breast Neoplasms/pathology , Diagnosis, DifferentialABSTRACT
No disponible
Subject(s)
Humans , Female , Aged , Tuberculosis, Cutaneous/diagnosis , Mycobacterium tuberculosis/isolation & purification , Polymerase Chain ReactionABSTRACT
Two hundred forty-seven healthy newborns were investigated in a prospective cohort descriptive study. Information on phenotype and obstetric and parental history was collected. A positive association was found between erythema toxicum neonatorum and season of birth (spring and summer), whereas parental history of any skin disease was related to a lower frequency of this eruption.
Subject(s)
Delivery, Obstetric/statistics & numerical data , Skin Diseases/epidemiology , Adult , Dermatitis, Atopic/epidemiology , Female , Humans , Infant, Newborn , Infant, Newborn, Diseases/epidemiology , Male , Prevalence , Prospective Studies , Seasons , Spain/epidemiologySubject(s)
Breast Neoplasms/pathology , Carcinoma, Ductal, Breast/secondary , Diagnostic Errors , Estrogens , Herpes Zoster/diagnosis , Neoplasms, Hormone-Dependent/secondary , Progesterone , Skin Neoplasms/secondary , Aged , Biopsy , Breast Neoplasms/therapy , Carcinoma, Ductal, Breast/chemistry , Carcinoma, Ductal, Breast/diagnosis , Combined Modality Therapy , Female , Humans , Neoplasms, Hormone-Dependent/chemistry , Neoplasms, Hormone-Dependent/diagnosis , Neoplasms, Hormone-Dependent/pathology , Skin Neoplasms/chemistry , Skin Neoplasms/diagnosis , Skin Neoplasms/pathology , ThoraxSubject(s)
Skin Ulcer/microbiology , Tuberculosis, Cutaneous/diagnosis , Aged , Female , Humans , Shoulder , Skin Ulcer/pathologyABSTRACT
Aplasia cutis congenita (ACC) is a congenital defect consisting of a circumscribed absence of skin that usually involves the scalp. The etiology is uncertain, and several teratogenic agents such as methimazole have been involved. We report two cases of ACC and other anomalies in newborns exposed to methimazole during pregnancy.
Subject(s)
Antithyroid Agents/adverse effects , Ectodermal Dysplasia/chemically induced , Graves Disease/drug therapy , Methimazole/adverse effects , Prenatal Exposure Delayed Effects/chemically induced , Adult , Female , Humans , Infant, Newborn , Male , Pregnancy , Propylthiouracil/adverse effects , Scalp/abnormalitiesABSTRACT
A 72-year-old Caucasian woman without remarkable medical history presented with an asymptomatic bilateral periocular swelling, which had been present for 2 months. Physical examination showed symmetric indurated periocular erythematous plaques (Figure 1). Biopsy of a skin lesion revealed aggregates of vacuoles of different sizes (Figure 2) surrounded by a prominent inflammatory infiltrate constituted by macrophages, lymphocytes, neutrophils, and granulomatous foreign body reaction throughout the reticular dermis and hypodermis. These histological findings were consistent with the injection of an oily foreign substance. The patient denied the self-induced nature of the lesions, so she was referred for psychiatric evaluation and admitted having self-injected mineral oil as an impulsive attempt to get attention from her family. She was diagnosed with borderline personality disorder (BPD) and started treatment with oral fluoxetine, showing a rapid decrease of impulsive behavior and anxiety from the second week with a mean dose of 80 mg/d.
