ABSTRACT
Caso clínico: Mujer de 29 años de edad, que refería cefalea de varios días de evolución, con posterior pérdida de visión y dolor en su ojo izquierdo. Como antecedentes: diabetes mellitus tipo 1, de 3 años de evolución y ser inmigrante de Ecuador. El examen fundoscópico reveló un papiledema. La reacción en cadena de la polimerasa (PCR) en líquido cefalorraquídeo fue positiva para Mycobacterium tuberculosis (MTB). Posteriormente al tratamiento con tuberculostáticos presentó una mejoría marcada. Discusión: La tercera parte de la población mundial presenta una infección latente por MTB; existe una comorbilidad entre diabetes mellitus y tuberculosis, principalmente en los países en vías de desarrollo (AU)
Case report: The case is presented of a 29-year-old woman who complained of headache over a period of several days, with loss of visual acuity and pain in her left eye. She had a 3-year history of type 1 diabetes mellitus, and was an immigrant from Ecuador. The funduscopic examination revealed a papilledema. The polymerase chain reaction (PCR) study of the cerebrospinal fluid was positive for Mycobacterium tuberculosis (MTB). She showed a marked improvement after treatment with anti-TB drugs. Discussion: About a third of the world's population has a latent infection of MTB, comorbidity between diabetes mellitus and tuberculosis has been reported, particularly in undeveloped countries (AU)
Subject(s)
Humans , Female , Adult , Papilledema/etiology , Tuberculosis, Meningeal/complications , Diabetes Mellitus, Type 1/complications , Polymerase Chain ReactionABSTRACT
CASE REPORT: The case is presented of a 29-year-old woman who complained of headache over a period of several days, with loss of visual acuity and pain in her left eye. She had a 3-year history of type 1 diabetes mellitus, and was an immigrant from Ecuador. The funduscopic examination revealed a papilledema. The polymerase chain reaction (PCR) study of the cerebrospinal fluid was positive for Mycobacterium tuberculosis (MTB). She showed a marked improvement after treatment with anti-TB drugs. DISCUSSION: About a third of the world's population has a latent infection of MTB, comorbidity between diabetes mellitus and tuberculosis has been reported, particularly in undeveloped countries.
Subject(s)
Diabetes Mellitus, Type 1/complications , Papilledema/etiology , Tuberculosis, Meningeal/diagnosis , Adult , Antitubercular Agents/therapeutic use , Atrophy , Cerebrospinal Fluid/microbiology , Developing Countries , Drug Therapy, Combination , Ecuador/ethnology , False Negative Reactions , Female , Humans , Immunocompromised Host , Isoniazid/therapeutic use , Latent Tuberculosis/epidemiology , Mycobacterium tuberculosis/isolation & purification , Ophthalmoscopy , Optic Nerve/pathology , Rifampin/therapeutic use , Spinal Puncture , Tuberculin Test , Tuberculosis, Meningeal/cerebrospinal fluid , Tuberculosis, Meningeal/complicationsSubject(s)
Cataract/complications , Lasers , Lens Capsule, Crystalline/pathology , Optic Nerve Diseases/diagnosis , Tomography, Optical Coherence/methods , Visual Field Tests/methods , Epithelial Cells/pathology , Fibrosis , Humans , Lens Capsule, Crystalline/surgery , Metaplasia , Optic Nerve/pathology , Optic Nerve Diseases/complications , Pseudophakia/complications , Retina/pathologyABSTRACT
No disponible
Subject(s)
Pseudophakia/complications , Pseudophakia/diagnosis , Eye Diseases/complications , Eye Diseases/diagnosis , Visual Acuity/physiology , Tomography, Optical Coherence/methods , Optic Nerve/pathology , Optic Nerve/physiopathology , Visual Acuity , Visual Acuity/genetics , Visual Acuity/immunology , Refractive Errors/complications , Visual Field Tests/methods , Visual Field Tests/trends , Tomography, Optical Coherence/trendsABSTRACT
PURPOSE: To evaluate the influence of posterior capsular opacification (PCO) on macular optical coherence tomography (OCT) imaging quality and measurements of macular retinal thickness. METHODS: In this prospective interventional case series, 32 eyes of 23 patients with PCO were recruited. Best-corrected visual acuity (BCVA), a complete ophthalmologic assessment, and macular OCT scans (OCT Stratus 3000) before and after Nd:YAG capsulotomy were performed. Two parameters for image quality (signal strength (SS) and number of tomographic messages) and 10 macular retinal thickness measurements were compared. Spearman correlations between BCVA and SS and macular retinal thickness measurements before and after capsulotomy were also performed. RESULTS: PCO removal was associated with an increase of best-corrected visual acuity (p<0.0001). The mean SS (n=32) went from 3.34+/-2.31 to 6.38+/-1.93 (p<0.0001) after Nd:YAG capsulotomy. The SS improved in 26 of 32 eyes. No significant difference between mean preoperative and postoperative macular retinal thickness measurements was observed (p<0.05) in valuable scans. Before capsulotomy, a correlation existed between BCVA and SS. After capsulotomy this correlation was no longer found. CONCLUSIONS: OCT image quality is influenced by PCO. Nd:YAG capsulotomy results in a measurable improvement in SS and improvement in the number of valuable examinations. Valuable OCT scans in patients with PCO seem to yield reliable measurements of macular retinal thickness even in the presence of severe PCO. The correlation between BCVA and SS before capsulotomy suggests that the SS could be considered an objective indicator of the degree of PCO.
