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1.
Brain ; 145(6): 1906-1915, 2022 06 30.
Article in English | MEDLINE | ID: mdl-35472071

ABSTRACT

Persistent symptoms following a minor head injury can cause significant morbidity, yet the underlying mechanisms for this are poorly understood. The shortcomings of the current terminology that refer to non-specific symptom clusters is discussed. This update considers the need for a multi-dimensional approach for the heterogenous mechanisms driving persistent symptoms after mild traumatic brain injury. Relevant pathophysiology is discussed to make the case for mild traumatic brain injury to be conceptualized as an interface disorder spanning neurology, psychiatry and psychology. The relevance of pre-injury factors, psychological co-morbidities and their interaction with the injury to produce persistent symptoms are reviewed. The interplay with psychiatric diagnoses, functional and somatic symptom disorder presentations and the influence of the medicolegal process is considered. The judicious use and interpretation of investigations given the above complexity is discussed, with suggestions of how the explanation of the diagnostic formulation to the patient can be tailored, including insight into the above processes, to aid recovery. Moving beyond the one-dimensional concept of 'postconcussional syndrome' and reframing the cause of persistent symptoms following mild traumatic brain injury in a bio-psycho-socio-ecological model will hopefully improve understanding of the underlying contributory mechanistic interactions and facilitate treatment.


Subject(s)
Brain Concussion , Mental Disorders , Neurology , Post-Concussion Syndrome , Psychiatry , Brain Concussion/diagnosis , Humans , Mental Disorders/etiology , Post-Concussion Syndrome/diagnosis , Post-Concussion Syndrome/etiology , Post-Concussion Syndrome/psychology
2.
Pract Neurol ; 22(2): 129-137, 2022 Apr.
Article in English | MEDLINE | ID: mdl-34906998

ABSTRACT

Post-traumatic amnesia is the transient state of altered brain function that may follow a traumatic brain injury. At a practical level, an individual has emerged from post-traumatic amnesia when he or she is fully orientated and with return of continuous memory. However, the clinical manifestations are often more complex, with numerous cognitive domains commonly affected, as well as behaviour. In the acute setting, post-traumatic amnesia may easily go unrecognised; this is problematic as it has important implications for both immediate management and for longer-term prognosis. We therefore recommend its careful clinical assessment and prospective evaluation using validated tools. Patients in post-traumatic amnesia who have behavioural disturbance can be particularly challenging to manage. Behavioural and environmental measures form the mainstay of its treatment while avoiding pharmacological interventions where possible, as they may worsen agitation. Patients need assessing regularly to determine their need for further rehabilitation and to facilitate safe discharge planning.


Subject(s)
Brain Injuries, Traumatic , Psychotic Disorders , Amnesia/etiology , Amnesia/psychology , Brain Injuries, Traumatic/complications , Brain Injuries, Traumatic/psychology , Female , Humans , Prognosis
3.
Psychother Res ; 20(4): 447-61, 2010 Jul.
Article in English | MEDLINE | ID: mdl-20665340

ABSTRACT

This study investigated the experiences of people who received a contemporary form of cognitive therapy for distressing voices. Eighteen people who heard distressing voices participated in an 8-session person-based cognitive therapy (PBCT) group and were then interviewed to elicit their experiences from the group. Data were gathered during a series of five posttherapy focus groups based on a semistructured interview schedule. A grounded theory approach was used to generate, work with, and understand the data. Four categories emerged: two representing the context for reflection and change and two representing the acceptance of voices and self and the changing sense of self. The conceptual and clinical implications of the findings are discussed.


Subject(s)
Cognitive Behavioral Therapy/methods , Hallucinations/therapy , Adaptation, Psychological , Adult , Cognitive Behavioral Therapy/standards , Emotions , Female , Focus Groups , Hallucinations/psychology , Humans , Interviews as Topic , Male , Middle Aged , Psychotherapy, Group/methods , Social Isolation , Stress, Psychological/psychology
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