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J Am Vet Med Assoc ; 225(8): 1237-41, 2004 Oct 15.
Article in English | MEDLINE | ID: mdl-15521447

ABSTRACT

OBJECTIVE: To determine duration of administration, complications, and frequency of aortic thromboembolism associated with administration of low molecular weight heparin (dalteparin) in cats. DESIGN: Retrospective study. ANIMALS: 57 cats treated with dalteparin PROCEDURE: Data were recorded from the medical records of cats treated with dalteparin, and owners were contacted by telephone for information regarding ease of administration and possible adverse effects. RESULTS: Dalteparin was easily administered by owners. Median dose was 99 U/kg (45 U/lb) once or twice daily. Bleeding complications were infrequent. Of 43 cats with cardiomyopathy that received owner-administered dalteparin for a median follow-up time of 172 days, 8 cats developed documented or possible arterial thromboembolism. CONCLUSIONS AND CLINICAL RELEVANCE: Dalteparin was easily administered by owners and was well tolerated by cats. Whether dalteparin administration can reduce the frequency or severity of arterial thromboembolism is not yet known.


Subject(s)
Anticoagulants/therapeutic use , Cat Diseases/drug therapy , Heparin, Low-Molecular-Weight/therapeutic use , Thromboembolism/veterinary , Animals , Anticoagulants/adverse effects , Blood Coagulation/drug effects , Cats , Female , Heparin, Low-Molecular-Weight/adverse effects , Injections, Subcutaneous/veterinary , Male , Retrospective Studies , Thromboembolism/drug therapy , Treatment Outcome
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