1.
Appl Microbiol
; 25(3): 325-6, 1973 Mar.
Article
in English
| MEDLINE
| ID: mdl-4349184
ABSTRACT
An antibody-free human serum fraction has been prepared by ammonium sulfate precipitation. This fraction can be substituted for whole serum in the production of optimal yields of interferon by induced human leukocytes.
Subject(s)
Immune Sera , Interferons/biosynthesis , Leukocytes/metabolism , Ammonium Sulfate , Amnion , Chemical Precipitation , Chromatography, Gel , Culture Techniques , Electrophoresis, Polyacrylamide Gel , Humans , Immunodiffusion , Immunoglobulins/isolation & purification , Interferons/analysis , Parainfluenza Virus 1, Human , Poliovirus/growth & development
2.
Proc Soc Exp Biol Med
; 142(1): 46-9, 1973 Jan.
Article
in English
| MEDLINE
| ID: mdl-4345724
Subject(s)
Blood , Culture Media , Interferons/biosynthesis , Leukocytes/metabolism , Blood Proteins/analysis , Cells, Cultured , Electrophoresis, Polyacrylamide Gel , Humans , Immunoglobulin A/analysis , Immunoglobulin G/analysis , Immunoglobulin M/analysis , Immunoglobulins/analysis , Interferons/analysis , Interferons/isolation & purification , Interferons/pharmacology , Leukocytes/microbiology , Poliovirus/drug effects , Respirovirus/growth & development
3.
Infect Immun
; 6(5): 886-8, 1972 Nov.
Article
in English
| MEDLINE
| ID: mdl-4564788
ABSTRACT
An interferon-inducing RNA, SK&F 42319, obtained from a lysate of phage-infected Escherichia coli, protected mice against Vibrio cholerae infection. This nonspecific protection was not attributable to endotoxin contamination.
Subject(s)
Bacteriophages , Escherichia coli/metabolism , RNA, Bacterial/pharmacology , Vibrio/immunology , Animals , Endotoxins/pharmacology , Interferon Inducers/pharmacology , Liver/enzymology , Male , Mice , Tryptophan Oxygenase/metabolism , Vibrio Infections/immunology
4.
Proc Soc Exp Biol Med
; 139(2): 455-60, 1972 Feb.
Article
in English
| MEDLINE
| ID: mdl-4333783
Subject(s)
Antiviral Agents/pharmacology , Indoles/pharmacology , Triazines/pharmacology , Cell Line/microbiology , Depression, Chemical , HeLa Cells/metabolism , HeLa Cells/microbiology , Humans , Lung , Poliovirus/drug effects , RNA, Neoplasm/biosynthesis , RNA, Viral/biosynthesis , Rhinovirus/drug effects , Tritium , Uridine/metabolism , Virus Replication/drug effects
5.
Biochim Biophys Acta
; 132(1): 15-26, 1967 Jan 11.
Article
in English
| MEDLINE
| ID: mdl-6030345
6.
Biochim Biophys Acta
; 132(1): 27-32, 1967 Jan 11.
Article
in English
| MEDLINE
| ID: mdl-6030357