1.
J Thorac Cardiovasc Surg
; 69(6): 870-3, 1975 Jun.
Article
in English
| MEDLINE
| ID: mdl-1134112
ABSTRACT
A study was designed to evaluate the hemodynamic effects of massive doses of methylprednisolone (30 mg. per kilogram) during cardiopulmonary bypass at normothermia and hypothermia. In 427 patients studied, significantly less vasoconstriction (p less than 0.01) and improved perfusion flows (p less than 0.0005) were obtained at comparable pressure levels in the steroid-treated group (272 patients) compared with the control group (155 patients). Because of these measured parameters, methylprednisolone should be considered a valuable adjunct to improving tissue perfusion during cardiopulmonary bypass.
Subject(s)
Cardiopulmonary Bypass , Extracorporeal Circulation , Methylprednisolone/pharmacology , Anesthesia, General , Aortic Valve/surgery , Blood Pressure/drug effects , Body Temperature , Coronary Vessels/surgery , Heart Septal Defects, Atrial/surgery , Humans , Hypothermia, Induced , Length of Stay , Mitral Valve/surgery , Perfusion , Vascular Resistance/drug effects
2.
J Thorac Cardiovasc Surg
; 58(1): 92-4, 1969 Jul.
Article
in English
| MEDLINE
| ID: mdl-5790443
3.
Postgrad Med
; 43(3): 203-9, 1968 Mar.
Article
in English
| MEDLINE
| ID: mdl-5650979
Subject(s)
Heart Block/therapy , Pacemaker, Artificial , Adult , Aged , Humans , Methods , Middle Aged
4.
Ann Surg
; 165(1): 1-9, 1967 Jan.
Article
in English
| MEDLINE
| ID: mdl-6018294
