ABSTRACT
Oral squamous cell carcinoma (OSCC) is a complex disease with heterogeneity in its clinical and pathological presentation as well as phenotypic and biologic behavior. Despite tremendous advancements in the field of genomics and technology, this particular entity still continues to contribute significantly to the mortality rates worldwide.1 Research that is directed toward the identification of molecular strategies adopted by cancer cells for survival, growth, invasion, and migration along with development of novel therapeutic schemes accordingly might help us to overcome this Delphic disease. In recent time, colossal development has been made in the field of cancer research exploring almost all the aspects that are linked with cell physiology. However, entering into totally new territory of cancer biology is the need of the hour that might solve the complex maze of cancer initiation and progression. One such area is Cajal bodies that are yet to be investigated for their role in oral carcinogenesis.
