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1.
Semin Ultrasound CT MR ; 43(4): 293-310, 2022 Aug.
Article in English | MEDLINE | ID: mdl-35738815

ABSTRACT

Virtual non-contrast (VNC) imaging is a post-processing technique generated from contrast-enhanced scans using dual-energy computed tomography (DECT). It is generated by removing iodine from imaging acquired at multiple energies. Myriad clinical studies have shown its ability to diagnose the various abdominal and pelvic pathologies discussed in the article. VNC is also a problem-solving tool for characterizing incidentally detected lesions ("incidentalomas"), often decreasing the need for additional follow-up imaging. It also obviates the multiphase image acquisitions to evaluate hematuria, hepatic steatosis, aortic endoleaks, and gastrointestinal bleeding by generating image datasets from different tissue attenuation values. The scope of this article is to provide an overview of various applications of VNC imaging obtained by DECT in the abdomen and pelvis.


Subject(s)
Radiography, Dual-Energy Scanned Projection , Tomography, X-Ray Computed , Abdomen/diagnostic imaging , Contrast Media , Humans , Pelvis/diagnostic imaging , Radiography, Dual-Energy Scanned Projection/methods , Retrospective Studies , Tomography, X-Ray Computed/methods
2.
Semin Ultrasound CT MR ; 43(4): 355-363, 2022 Aug.
Article in English | MEDLINE | ID: mdl-35738821

ABSTRACT

In recent years, there has been increased utilization of Dual-energy CT (DECT) in diagnostic imaging, mainly due to a reduction of effective radiation dose and lower intravenous contrast dose requirement in DECT imaging compared to conventional CT. A comprehensive imaging protocol and teamwork involving technologists and radiologists are needed to successfully implement DECT in clinical practice. At the same time, insight into the direct and indirect expenditures incurred is critical for rendering a cost-effective service to the patient and institution. This paper focuses on introducing the foundations of DECT to the readers and discusses the impediments encountered during the implementation of DECT in clinical practice. Potential solutions to these challenges are also proposed.


Subject(s)
Radiography, Dual-Energy Scanned Projection , Humans , Radiation Dosage , Radiography, Dual-Energy Scanned Projection/methods , Tomography, X-Ray Computed/methods
3.
Abdom Radiol (NY) ; 47(12): 4032-4041, 2022 12.
Article in English | MEDLINE | ID: mdl-35347385

ABSTRACT

Bladder pheochromocytomas (PCCs) are rare tumors that account for 0.06% of all bladder tumors and makeup 1% of all PCCs. Most PCCs are functional, and they secrete catecholamines that lead to clinical symptoms such as paroxysmal hypertension, headaches, palpitations, and sweating. However, some are nonfunctional and asymptomatic and are hence difficult to diagnose. Cystoscopy and biopsy should not be performed when bladder PCCs are suspected. They may provoke a hypertensive crisis if preventative antiadrenergic blockers are not administered prior to the procedure. The diagnostic workup begins with obtaining blood or urine catecholamine and catecholamine metabolite values to make a presumptive diagnosis of bladder PCC. Computed tomography (C.T.) and magnetic resonance imaging (MRI) are then used to localize and stage the tumor for surgical resection. MRI, due to its superior soft tissue resolution and the ability to use multiparametric MRI (mpMRI) to differentiate between layers of the bladder wall and from other bladder masses, is the optimal imaging modality to detect extra-adrenal bladder PCCs and determine locoregional staging. Once antiadrenergic medications are given, the tumor is resected, and the diagnosis is confirmed histologically. However, the differential diagnosis of bladder PCC often gets overlooked, leading to surgical resection in the absence of antiadrenergic medications, increasing the chances of a fatal hypertensive crisis. This makes MRI an essential diagnostic tool for staging bladder PCCs before surgery. This review discusses the indications for MRI in bladder PCCs and describes findings from these tumors on various MRI sequences and when to use them. We also discuss how MRI can differentiate bladder PCCs from other bladder neoplasms.


Subject(s)
Adrenal Gland Neoplasms , Pheochromocytoma , Urinary Bladder Neoplasms , Humans , Pheochromocytoma/pathology , Urinary Bladder/pathology , Adrenal Gland Neoplasms/surgery , Magnetic Resonance Imaging/methods , Catecholamines , Urinary Bladder Neoplasms/pathology , Adrenergic Antagonists
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