[The humoral immunity indices and complement functional activity in salmonellosis during the dynamics of the disease]. / Nekotorye pokazateli gumoral'nogo immuniteta i funktsional'naia aktivnost' komplementa pri sal'monelleze v dinamike zabolevaniia.

In 65 patients with bacteriologically confirmed gastrointestinal salmonellosis of moderate severity (41 males and 24 females) the disease in an acute phase was characterized by activation of complement system and specific antibody formation, by a growth in the levels of IgA, G and M. In early convalescence IgA and IgM remained high, IgG in females returned to normal, in males was still high. An inverse correlation was found between functional activity of complement components C3, C4 and C5 and levels of IgM, IgG.

[Experience with the autovaccinal treatment of chronic carriers of typhoid bacteria]. / Opyt lecheniia autovaktsinoi khronicheskikh nositelei briushnotifozynkh bakterii.

Considering bacterial carriership as a special form of typhoid infection inducing the allergic transformation of the body with the development of delayed type hypersensitivity and believing that vaccinal therapy might be the most promising method for treating the states of this kind, the authors used autovaccine, introduced by the method of epicutaneous electrophoresis in accordance with Alisov's scheme, for the treatment of chronic carriers of typhoid bacteria. The subsequent prolonged (up to 20 years) observation of the carriers revealed that the release of the infective agents became less intensive and the number of persistent carriers decreased 2.5 times as compared with the control group of carriers treated with antibiotics and roborants. The results of the study of morphological changes occurring in the mucous membrane of the small intestine of the carriers indicated that after complex treatment the inflammatory process decreased and in some carriers disappeared.