ABSTRACT
Foreign protein injections (hyposensitization) given for one year to human asymptomatic asthmatics did not increase their serum total lipids or lipoprotein levels, as they apparently did in rabbits fed a lipid-rich, cholesterol-poor diet. Serum total protein and immunoglobulin levels for IgA, IgM and IgG for the asthmatics and controls were no different.
Subject(s)
Asthma/blood , Desensitization, Immunologic , Lipids/blood , Lipoproteins/blood , Adolescent , Adult , Asthma/therapy , Blood Proteins/analysis , Child , Child, Preschool , Cholesterol/blood , Female , Humans , Immunoglobulins/analysis , Lipoproteins, HDL/blood , Lipoproteins, LDL/blood , Lipoproteins, VLDL/blood , Male , Parents , Time Factors , Triglycerides/bloodABSTRACT
Hypersensitivity pneumonitis, a disease caused by repetitive inhalation of nonviable organic dust, is increasingly recognized as a cause of acute and chronic lung disease in both children and adults. Twenty-one of 32 children and adults who went on a hay ride in Arkansas developed this disease. These cases are reported. The clinical manifestations, pathology, differential diagnosis, treatment, and immunologic aspects of the disease are reviewed.
Subject(s)
Antigens, Fungal , Dust , Hypersensitivity/complications , Pneumonia/etiology , Acute Disease , Adolescent , Adult , Arthus Reaction/diagnosis , Child , Chronic Disease , Female , Humans , Hypergammaglobulinemia/etiology , Hypersensitivity/immunology , Hypersensitivity/therapy , Immunodiffusion , Male , Pneumonia/immunology , Pneumonia/therapy , Skin TestsABSTRACT
An immunofluorescent test using ragweed pollen grains for identification of immunolglobulin type-specific rag weed antibodies is described. The test measured effectively antibody specificity produced by immunotherapy with Allpyral. Repeating the test after ragweed inhibition and the use of an unrelated pollen grain verified the specificity of the test.
