ABSTRACT
Turmeric has faced authenticity issues as instances of economic-adulterations to reduce the cost. We used carbon-14 and HPLC analyses as complementary methods to verify "all-natural" label claims of commercial dietary supplements containing turmeric ingredients. A high percentage of curcumin-to-curcuminoids value was used as an indicator to imply the presence of synthetic curcumin. However, using the HPLC method alone did not provide direct evidence of curcuminoids' natural origin, whereas using only the carbon-14 method cannot test for potency label claims and determine which constituent(s) contain 14C radiocarbon. By analyzing results from both methods, a significant correlation between the percentage of curcumin-to-curcuminoids and % biobased carbon (Pearson's r = -0.875, p < 0.001) indicated that synthetic curcumin was greatly attributed to determined synthetic ingredients. Only four out of the 14 samples analyzed supported authentic label claims. This orthogonal testing strategy showed its potential for the quality control of turmeric products.
Subject(s)
Curcuma , Curcumin , Carbon Radioisotopes , Curcumin/analysis , Diarylheptanoids , Dietary Supplements , Plant ExtractsABSTRACT
Across food and supplement industries, there is a growing trend toward products comprised of natural ingredients. As manufacturers strive to offer "natural" products to consumers, adulteration of ingredients with cheaper synthetic alternatives becomes a concern. This perspective highlights the application of carbon-14 analysis to screen for potential adulteration of natural ingredients, such as garlic oil. Carbon-14 testing determines if a product is comprised of solely plant- or animal-based ingredients by measuring the percentage of biomass versus petrochemical-derived sources. Through comparison to other analytical techniques used for quality control, carbon-14 testing stands out as being able to detect petrochemical-derived nature-identical compounds.
