1.
Eksp Klin Farmakol
; 59(5): 3-5, 1996.
Article
in Russian
| MEDLINE
| ID: mdl-9026206
ABSTRACT
A complex of special tests which took into account the coupling of the specific physiological responses with individual subtypes of muscarinic cholinoceptors, and radioligand analysis showed the predominance of M3- and M2-subtype presynaptic receptors in the rat brain hemispheres. The autoreceptors regulating the presynaptic release of acetylcholine are related mainly to the M2-subtype and account for the smaller part of the mixed population of presynaptic receptors.
Subject(s)
Receptors, Cholinergic/classification , Receptors, Presynaptic/classification , Animals , Arecoline/pharmacology , Brain/drug effects , Brain/physiology , Cholinergic Antagonists/pharmacology , Dichlorvos/toxicity , Drug Interactions , Female , Male , Muscarinic Agonists/pharmacology , Pilocarpine/pharmacology , Radioligand Assay , Rats , Receptors, Cholinergic/drug effects , Receptors, Cholinergic/physiology , Receptors, Presynaptic/antagonists & inhibitors , Receptors, Presynaptic/drug effects , Receptors, Presynaptic/physiology , Salivation/drug effects , Tremor/chemically induced
2.
Biull Eksp Biol Med
; 122(7): 75-7, 1996 Jul.
Article
in Russian
| MEDLINE
| ID: mdl-9303708