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[Evaluation of changes in erythrocyte functions and iron metabolism in patients with chronic renal failure treated by peritoneal dialysis]. / Otsenka izmenenii pokazatelei krasnoi krovi i obmena zheleza u bol'nykh khronicheskoi pochechnoi nedostatochnost'iu, nakhodiashchikhsia na peritoneal'nom dialize.

Romanova, L A; Lugovskaia, S A; Shutov, E V; Shmarov, D A; Korovina, V I; Gorodnicheva, V F; Kozinets, G I.

Klin Lab Diagn ; (6): 24, 33-6, 2001 Jun.

Article in Russian | MEDLINE | ID: mdl-11521593

Subject(s)

Anemia, Hemolytic , Erythrocytes/metabolism , Iron/blood , Kidney Failure, Chronic/blood , Anemia, Hemolytic/blood , Anemia, Hemolytic/etiology , Erythrocyte Count , Erythrocyte Volume , Erythrocytes/pathology , Erythropoietin/therapeutic use , Humans , Kidney Failure, Chronic/complications , Kidney Failure, Chronic/therapy , Peritoneal Dialysis/adverse effects , Recombinant Proteins , Transferrin/metabolism

[Hemopoiesis in chronic myelomonocytic leukemia]. / Gemopoéz pri khronicheskom mielomonotsitarnom leikoze.

Lugovskaia, S A; Morozova, V T; Lukina, E A; Kozlovskaia, A S; Gorodnicheva, V F; Sysoeva, E P.

Klin Lab Diagn ; (10): 8-11, 1998 Oct.

Article in Russian | MEDLINE | ID: mdl-9864996

ABSTRACT

Hemopoiesis and functional activity of monocytes were assessed in 30 patients with chronic myelomonocytic leukemia (CMML). Changes in haemogram in CMML are characterized by anemia, thrombocytopenia, normal or increased count of leukocytes with absolute monocytosis and increased count of young granulocytes. Bone marrow hemopoiesis is characterized by enhanced proliferation of cellular elements of granulocytopoiesis and monocytes, suppressed erythropoiesis and megakaryocytopoiesis. Dysplastic changes are most expressed in the erythrocytic stem cells. Studies of lysosomal enzymes showed their increased activity in monocytes of CMML patients.

Subject(s)

Hematopoiesis , Leukemia, Myelomonocytic, Chronic/blood , Leukemia, Myelomonocytic, Chronic/pathology , Adult , Aged , Aged, 80 and over , Cell Differentiation , Cell Division , Erythrocytes/pathology , Esterases/blood , Female , Humans , Leukemia, Myelomonocytic, Chronic/physiopathology , Male , Middle Aged , Phosphoric Monoester Hydrolases/blood

[The prognostic criteria in the primary myelodysplastic syndrome]. / Prognosticheskie kriterii pri pervichnom mielodisplasticheskom sindrome.

Tsvetaeva, N V; Zavadenko, M A; Popov, V Iu; Glasko, E N; Gorodnicheva, V F; Levina, A A; Pochtar', M E; Vinogradova, O Iu; Alisova, A M; Frank, G A; Khoroshko, N D.

Ter Arkh ; 68(7): 37-42, 1996.

Article in Russian | MEDLINE | ID: mdl-8928070

ABSTRACT

Basing on computer processing of 126 primary clinical and laboratory parameters obtained from 92 patients with myelodysplasia and using multifactorial regression analysis, the authors have developed prognostic models of life span and probability of transformation into acute leukemia. The model of life span enabled recognition of 3 prognostic groups of myelodysplasia patients: of high (median 10 months), moderate (median 22 months) and low (median 35 months) risk. This makes it possible to prognosticate the disease and assume optimal therapeutic policy.

Subject(s)

Myelodysplastic Syndromes/mortality , Adult , Aged , Aged, 80 and over , Biopsy, Needle , Bone Marrow/pathology , Disease Progression , Female , Humans , Male , Middle Aged , Multivariate Analysis , Myelodysplastic Syndromes/pathology , Myelodysplastic Syndromes/therapy , Probability , Prognosis , Regression Analysis , Remission Induction , Risk Factors

[Extramedullary exacerbation of chronic myeloleukemia]. / Vnekostnomozgovoe obostrenie khronicheskogo mieloleikoza.

Frinovskaia, I V; Khokhlova, M P; Topchiashvili, Z A; Gorodnicheva, V F; Zakharova, A V.

Gematol Transfuziol ; 29(5): 51-3, 1984.

Article in Russian | MEDLINE | ID: mdl-6588014

Subject(s)

Leukemia, Myeloid/pathology , Spleen/pathology , Female , Humans , Middle Aged

[Cytochemical analysis of the blast cells in chronic myeloleukemia]. / Tsitokhimicheskii analiz blastnykh kletok pri khronicheskom mieloleikoze.

Frinovskaia, I V; Gorodnicheva, V F; Turkina, A G; Morozova, L F; Radzikhovskaia, R M.

Probl Gematol Pereliv Krovi ; 26(2): 13-5, 1981 Feb.

Article in Russian | MEDLINE | ID: mdl-6940115

Subject(s)

Bone Marrow/metabolism , Leukemia, Myeloid/metabolism , Leukocytes/metabolism , Bone Marrow Cells , Enzyme Activation , Glycogen/metabolism , Histocytochemistry , Humans , Lipid Metabolism , Naphthol AS D Esterase/metabolism , Peroxidases/metabolism

[Specific leukemic lesion of the nervous system in myelocytic leukemia]. / Spetsificheskoe leikemicheskoe porazhenie nervnoi sistemy pri khronicheskom mieloleikoze.

Frinovskaia, I V; Markarian, V G; Gorodnicheva, V F; Ivanova, T N; Protasova, T G.

Ter Arkh ; 50(5): 55-8, 1978.

Article in Russian | MEDLINE | ID: mdl-276947

Subject(s)

Leukemia, Myeloid/complications , Leukemia/etiology , Meningeal Neoplasms/etiology , Pia Mater , Adult , Female , Humans , Male , Middle Aged

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