ABSTRACT
The implementation of immunotherapy has radically changed the treatment of oncological patients. Currently, immunotherapy is indicated in the treatment of patients with head and neck tumors, melanoma, lung cancer, bladder tumors, colon cancer, cervical cancer, breast cancer, Merkel cell carcinoma, liver cancer, leukemia and lymphomas. However, its efficacy is restricted to a limited number of cases. The challenge is, therefore, to identify which subset of patients would benefit from immunotherapy. To this end, the establishment of immunotherapy response criteria and predictive and prognostic biomarkers is of paramount interest. In this report, a group of experts of the Spanish Society of Medical Oncology (SEOM), the Spanish Society of Medical Radiology (SERAM), and Spanish Society of Nuclear Medicine and Molecular Imaging (SEMNIM) provide an up-to-date review and a consensus guide on these issues (AU)
Subject(s)
Humans , Antineoplastic Agents, Immunological , Neoplasms/therapy , Consensus , Spain , Societies, Medical , Disease Progression , Response Evaluation Criteria in Solid Tumors , Neoplasms/diagnostic imaging , Neoplasms/immunologyABSTRACT
The implementation of immunotherapy has radically changed the treatment of oncological patients. Currently, immunotherapy is indicated in the treatment of patients with head and neck tumors, melanoma, lung cancer, bladder tumors, colon cancer, cervical cancer, breast cancer, Merkel cell carcinoma, liver cancer, leukemia and lymphomas. However, its efficacy is restricted to a limited number of cases. The challenge is, therefore, to identify which subset of patients would benefit from immunotherapy. To this end, the establishment of immunotherapy response criteria and predictive and prognostic biomarkers is of paramount interest. In this report, a group of experts of the Spanish Society of Medical Oncology (SEOM), the Spanish Society of Medical Radiology (SERAM), and Spanish Society of Nuclear Medicine and Molecular Imaging (SEMNIM) provide an up-to-date review and a consensus guide on these issues.
Subject(s)
Consensus , Immunotherapy/methods , Neoplasms/therapy , Societies, Medical , Disease Progression , Humans , Immune Checkpoint Inhibitors/therapeutic use , Immunotherapy/adverse effects , Medical Oncology , Neoplasms/diagnostic imaging , Neoplasms/immunology , Nuclear Medicine , Radiology , Response Evaluation Criteria in Solid Tumors , Spain , Treatment OutcomeABSTRACT
No disponible
Subject(s)
Humans , Female , Aged , Pneumonia, Aspiration/complications , Pneumonia, Aspiration/surgery , Subclavian Artery/pathology , Subclavian Artery , Gastroscopy/methods , Dyspnea/complications , Hypertension/complications , Atrial Fibrillation/complications , Radiography, Thoracic , Tomography/instrumentation , Tomography/methods , Deglutition Disorders/complications , Deglutition DisordersABSTRACT
No disponible
Subject(s)
Humans , Male , Aged , Birt-Hogg-Dube Syndrome/genetics , Birt-Hogg-Dube Syndrome/therapy , Birt-Hogg-Dube Syndrome , Lithiasis/complications , Lithiasis , Catheter Ablation/methods , Pulsed Radiofrequency Treatment/methods , Pulsed Radiofrequency Treatment , Hematuria/complications , Pain/complications , Pain/diagnosis , Pain/etiology , Pneumothorax/complications , Magnetic Resonance Imaging , Mutagenesis/physiology , Kidney NeoplasmsSubject(s)
Humans , Male , Adult , Pneumonia, Lipid/complications , Pneumonia, Lipid/therapy , Pneumonia, Lipid , Oxygen/therapeutic use , Adrenal Cortex Hormones/therapeutic use , Anti-Bacterial Agents/therapeutic use , Pneumonia, Lipid/drug therapy , Pneumonia, Lipid/physiopathology , Paraffin/adverse effects , Paraffin/toxicity , Dyspnea/complications , Dyspnea , Radiography, ThoracicABSTRACT
No disponible
Subject(s)
Humans , Tomography, Emission-Computed/trends , Tomography, X-Ray Computed/trends , Technological Development , Diagnostic ImagingABSTRACT
CASE REPORT: We report the case of a 44-year-old woman, with a history of cigarette smoking (60 per day) and hyperthyroidism. She presented a bilateral ocular ischemic syndrome, and a bilateral occlusive carotid artery disease which showed reverse ophthalmic artery flow that resulted in a steal phenomenon, characterized by a shunt to the low resistance intracranial circuits and reduction of blood flow to the eyes. DISCUSSION: Young patients with severe bilateral occlusive carotid artery disease may be at greater risk of developing ocular ischemic syndrome, while this reverse flow decreases the patient's risk of stroke and death.
Subject(s)
Carotid Artery, Internal/physiopathology , Carotid Stenosis/physiopathology , Collateral Circulation , Ischemia/physiopathology , Ophthalmic Artery/physiopathology , Adult , Blood Flow Velocity , Carotid Artery, Internal/diagnostic imaging , Carotid Stenosis/diagnostic imaging , Female , Hemodynamics , Humans , Radiography , Retinal Artery/physiopathology , Smoking/adverse effects , Visual AcuityABSTRACT
Caso clínico: Describimos el caso de una mujer de 44 años, fumadora de 60 cig./día y con antecedentes de hipertiroidismo. Presentó un síndrome de isquemia ocular en ambos ojos (AO) por oclusión de carótidas internas que originó un flujo retrógrado en ambas arterias oftálmicas, produciendo un fenómeno de robo caracterizado por un shunt a los circuitos intracraneales de baja resistencia y una reducción en el aporte sanguíneo a los ojos. Discusión: Los pacientes jóvenes con obstrucción carotídea bilateral severa tienen mayor riesgo de desarrollar un síndrome de isquemia ocular, mientras este flujo retrógrado parece reducir su riesgo de infarto cerebral o muerte (AU)
Case report: We report the case of a 44-year-old woman, with a history of cigarette smoking (60 per day) and hyperthyroidism. She presented a bilateral ocular ischemic syndrome, and a bilateral occlusive carotid artery disease which showed reverse ophthalmic artery flow that resulted in a steal phenomenon, characterized by a shunt to the low resistance intracranial circuits and reduction of blood flow to the eyes. Discussion: Young patients with severe bilateral occlusive carotid artery disease may be at greater risk of developing ocular ischemic syndrome, while this reverse flow decreases the patient’s risk of stroke and death (AU)
Subject(s)
Adult , Female , Humans , Collateral Circulation , Tobacco Use Disorder , Carotid Stenosis , Ophthalmic Artery , Retinal Artery , Blood Flow Velocity , Carotid Artery, Internal , Ischemia , Hemodynamics , Visual AcuityABSTRACT
Ewing's sarcoma is an uncommon malignancy that usually occurs in children. A case of Ewing's sarcoma of the mandible is presented, and the radiologic appearance is described, with special consideration given to the magnetic resonance imaging features.
