ABSTRACT
The erythron response to muscular training in 2-6-week old rats involved an increase in concentration of erythrocytes accompanied by no adequate enhancement of the hemoglobin synthesis. Changes of the erythrocyte morphometric indices were revealed. Erythropoiesis increased under the influence of muscular exercises. Quantitative changes of the bone marrow erythroid tissue are the basis of this response. The erythron seems to be able to produce and support only short adaptive erythrocytosis during muscular training in young rats, not the long-term adaptive reactions.
Subject(s)
Aging/physiology , Erythrocytes/physiology , Muscles/physiology , Physical Exertion/physiology , Animals , Erythrocyte Count , Erythrocyte Indices , Erythropoiesis/physiology , Female , Hematocrit , Hemoglobins/analysis , Male , Rats , Swimming , Time FactorsABSTRACT
Dynamic muscular exercises intensified the erythropoiesis within one week and the erythrocytosis within two weeks in rats. An increase in the marrow erythroid cells proliferative activity was the basis of this reaction. The dynamics of this index coincide with the blood reticulocyte concentration dynamics. The serum erythropoietin activity was found to increase considerably. These findings suggest that erythropoietin can increase the erythroid cells proliferative activity.
Subject(s)
Adaptation, Physiological , Muscles/physiology , Polycythemia/etiology , Animals , Blood Volume , Erythropoiesis , Erythropoietin/blood , Female , Hypoxia/blood , Hypoxia/physiopathology , Male , Mice , Mice, Inbred C57BL , Mice, Inbred CBA , Polycythemia/blood , Polycythemia/physiopathology , Rats , Swimming , Time FactorsSubject(s)
Adaptation, Physiological , Erythrocytes/physiology , Physical Exertion , 2,3-Diphosphoglycerate , Anemia/etiology , Anemia/physiopathology , Animals , Diphosphoglyceric Acids/blood , Erythropoiesis , Hemoglobins/physiology , Humans , Oxygen/blood , Polycythemia/etiology , Polycythemia/physiopathology , SportsSubject(s)
Muscles/physiology , Physical Conditioning, Animal/methods , Animals , Male , Rats , Research Design , Swimming , Time FactorsABSTRACT
Dynamic physical exercises cause erythrocytosis and an enhancement of total erythrocyte respiratory surface in rats, intensification of the erythropoiesis and an increase of reticulocyte and erythroblast concentration in the blood. Hyperplasia of the bone marrow erythroid cells and activation of extramedullary erythropoiesis were revealed, as well as the phases of this adaptation process.
