[Evaluation of plasmapheresis effectiveness in patients with psoriasis]. / Otsenka éffektivnosti plasmafereza u bol'nykh psoriazom.

A pronounced therapeutic effect of plasmapheresis recorded in 21 psoriasis patients correlated with changes in hemostasis and immune status supporting the conception of autoimmune origin of the disease. Using present-day methods of immunological and hemostatic investigation it becomes possible to manage the oriented correction which is an important factor in psoriasis therapy.

[Plasmapheresis in dermatology]. / Plazmaferez v dermatologii.

Overall 105 patients with different dermatoses were placed under observation. The patients received plasmapheresis (PA) treatment. PA was tolerated well by the majority of the patients, with the method efficacy amounting to 96%. PA eliminated disseminated intravascular coagulation which was initially seen in the majority of the patients, led to the normalization of hemostasis and microcirculation. At the same time PA exerted an immunocorrective action which showed up by a decrease of the most parameters of humoral and cellular immunity, the level of CIC, complement activity with a simultaneous rise of the phagocytic index, which may attest to macrophagal system activation.

[Plasmapheresis in the therapy of refractive forms of psoriasis]. / Plazmaferez v terapii refrakternykh form psoriaza.

Plasmapheresis efficacy was assessed in 18 patients with psoriasis running a prolonged and torpid course resistant to therapy administered before. Intermittent flow plasmapheresis method was employed. The course of treatment consisted of 5-8 sessions, 600-1050 ml of plasma was removed per session. Good effect was achieved in all the patients. Plasmapheresis was well tolerated, no grave side effects or complications were recorded.