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Design and synthesis of biotinylated DHMEQ for direct identification of its target NF-κB components.
Bioorg Med Chem Lett
; 21(21): 6293-6, 2011 Nov 01.
Article
in English
| MEDLINE
| ID: mdl-21945203
ABSTRACT
The design and synthesis of dehydroxymethylepoxyquinomicin (DHMEQ) derivatives were carried out to investigate the intracellular targets. The synthetic biotin probe exhibited membrane permeability and combined selectively with the target protein p65.