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Lab Chip ; 10(16): 2108-14, 2010 Aug 21.
Article in English | MEDLINE | ID: mdl-20556295

ABSTRACT

We present theoretical, numerical, and experimental analyses on the non-linear dynamic behavior of superparamagnetic beads exposed to a periodic array of micro-magnets and an external rotating field. The agreement between theoretical and experimental results revealed that non-linear magnetic forcing dynamics are responsible for transitions between phase-locked orbits, sub-harmonic orbits, and closed orbits, representing different mobility regimes of colloidal beads. These results suggest that the non-linear behavior can be exploited to construct a novel colloidal separation device that can achieve effectively infinite separation resolution for different types of beads, by exploiting minor differences in their bead's properties. We also identify a unique set of initial conditions, which we denote the "devil's gate" which can be used to expeditiously identify the full range of mobility for a given bead type.


Subject(s)
Ferrosoferric Oxide/chemistry , Magnetics/methods , Microspheres , Models, Theoretical , Algorithms , Nonlinear Dynamics , Particle Size
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