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1.
Medicine (Baltimore) ; 102(22): e33926, 2023 Jun 02.
Article in English | MEDLINE | ID: mdl-37266632

ABSTRACT

Hypertension is a leading cause of death worldwide. Hypertension is associated with poor sleep quality, which adversely affects physical and mental health, and can increase the incidence rate and mortality of cardiovascular disease, cancer, and depression. This study aimed to investigate the prevalence of the factors related to poor sleep quality in hypertensive patients in Shandong Province, China. This cross-sectional study of adult patients with hypertension from August 2020 to February 2021was conducted in 10 cooperative hospitals in Shandong Province, China. Information was collected in the form of a questionnaire. In this study, Pittsburgh sleep quality index was used to evaluate sleep quality. A multivariate logistic regression model was used to analyze the risk of poor sleep quality. Variables with a P value < 0.05 and a 95% confidence interval (CI) were considered statistically significant. A total of 528 patients with hypertension were included, ranging in age from 31 to 90 years old. The prevalence of poor sleep quality among study participants with hypertension was 319 (60.4%) (95% CI: 0.562-0.646). Female gender (adjusted odds ratios [AOR] = 3.231; 95% CI: 2.194-4.757), stage III blood pressure (AOR = 2.142; 95% CI: 1.108-4.141), mental labor, and labor both physical and mental (AOR = 1.639; 95% CI:1.03-2.611 and AOR = 1.632; 95% CI: 1.030-2.584), unstable marriage (AOR = 3.203; 95% CI: 1.026-9.997) and the very Low-density Lipoprotein (odds ratios = 0.776; 95% CI: 0.649-0.928) were significantly associated with poor sleep quality. This study preliminarily showed that poor sleep quality was a common problem in hypertensive patients, and more than half of the hypertensive patients had poor sleep quality. Poor sleep quality was significantly correlated with gender, hypertension level, occupation, marital status, and the very Low-density Lipoprotein. Considering the negative impact of sleep quality, appropriate strategies should be developed to prevent and treat poor sleep quality in hypertensive patients.


Subject(s)
Hypertension , Sleep Initiation and Maintenance Disorders , Humans , Adult , Female , Middle Aged , Aged , Aged, 80 and over , Sleep Quality , Cross-Sectional Studies , Risk Factors , Hypertension/epidemiology , Lipoproteins, LDL , China/epidemiology , Prevalence
2.
Medicine (Baltimore) ; 101(42): e31250, 2022 Oct 21.
Article in English | MEDLINE | ID: mdl-36281125

ABSTRACT

Sleep disorders have been shown to increase the risk of hypertension, while the relationship between night sleep latency and hypertension is less well-known. We aimed to investigate the association between night sleep latency and hypertension, as well as related sleep factors by gender in the Chinese population. We conducted a cross-sectional study of the relationship between night sleep latency and hypertension. The sample size included 619 consecutive hospitalized patients (M/F: 302/317, 64.01 ±â€…12.27 years). T test, Chi-square test, and ANOVA were performed to analyze baseline data and intergroup comparisons. Spearman correlation analysis was performed to find the interrelationships. Multivariate logistic regression analysis was performed to adjust for covariables. The findings showed hypertension patients had longer night sleep latency (P < .001). After adjusting for confounding factors, night sleep latency was positively correlated with hypertension in both men and women (odds ratio: 1.065, 95% confidence interval: 1.044-1.087). Spearman correlation analysis suggested that night sleep latency was positively correlated with systolic blood pressure (r = 0.186, P < .001), diastolic blood pressure (r = 0.136, P < .001), sleep initiation time (r = 0.091, P = .023), and global Pittsburg Sleep Quality Index score (r = 0.371, P < .001), was negatively correlated with sleep duration (r = -0.186, P < .001), sleep time on weekdays (r = -0.183, P < .001), and sleep time on weekends (r = -0.179, P < .001). Longer night sleep latency was associated with an increased risk of hypertension in men and women, which might involve the pathological progression of hypertension along with other sleep factors.


Subject(s)
Hypertension , Sleep Wake Disorders , Male , Humans , Female , Sleep Latency , Cross-Sectional Studies , Sleep/physiology , Blood Pressure , Sleep Wake Disorders/complications , Risk Factors
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