ABSTRACT
A 12 year old boy with Burkitt's lymphoma developed severe hepatitis with hepatomegaly, subclinical jaundice, and a small rise in body temperature, associated with an important rise in SGPT and fall in prothrombin titres, 6 days after anticancer chemotherapy and 24 hours after halothane anaesthesia. Hepatitis A and B serology remained negative. This hepatic failure explained perhaps the unusually severe vincristine toxicity which gave rise to a polyneuritis with important sequelae. The association of halothane hepatitis with antimitotic drugs appeared particularly dangerous, and halothane should probably be avoided in all patients been given or about to be given anticancer chemotherapy.
Subject(s)
Anesthesia, Inhalation , Antineoplastic Agents/adverse effects , Chemical and Drug Induced Liver Injury/etiology , Halothane/adverse effects , Antineoplastic Agents/administration & dosage , Burkitt Lymphoma/drug therapy , Chemical and Drug Induced Liver Injury/pathology , Child , Drug Therapy, Combination , Humans , MaleABSTRACT
We study the chart of a new born with an oesophageal atresia. The weight of baby is two pounds and half and clinic look seems moderate: a gastrostomy and feeding jejunostomy are decided. After anaesthetic induction, intubation is impossible, and the tube knocks just under the vocal cords. Dilatations are no possible, and a straight approach is undertaken to cut stenosis and allow an extended intubation. Immediate and distant post operative series have brought the authors on abstract of their attitude after a review of literature.
Subject(s)
Cricoid Cartilage/abnormalities , Esophageal Atresia/complications , Laryngeal Cartilages/abnormalities , Constriction, Pathologic , Esophageal Atresia/surgery , Esophagus , Humans , Infant, Newborn , Intubation , Larynx/abnormalities , Male , MethodsSubject(s)
Cysts/congenital , Lung Diseases/congenital , Lung/abnormalities , Adenoma/congenital , Humans , Infant, Newborn , Lung/surgery , Lung Neoplasms/congenital , MaleABSTRACT
A 8 year-old girl was referred with a mucoepidermoid tumor of the bronchus. Surgery was tried before a mediastin left likeness; diagnosis resided in histology of the surgical piece. Reading of medical literature, very slight for children, corroborate difficulties of histologic classification of these tumors, and especially their doubtful forecast.
Subject(s)
Adenocarcinoma, Mucinous/pathology , Bronchial Neoplasms/pathology , Carcinoma, Squamous Cell/pathology , Bronchial Neoplasms/surgery , Child , Female , Humans , PrognosisABSTRACT
In work carried out over a period of two years in the department of anesthetics and intensive care of the Saint-Etienne University Hospital, the authors report their experience of neuroleptanalgesia using droperidol-dextromoramide in children in 104 cases. The observations may be divided up into 2 groups: - 1 group of children below the age of 2 years; - 1 group of children from 2 to 10 years. This study showed the side-effects and complications common to both groups, in particular, the extrapyramidal syndrome. Furthermore, the authors present their technique of administration.
Subject(s)
Anesthesia/methods , Neuroleptanalgesia/methods , Basal Ganglia Diseases/etiology , Child , Child, Preschool , Dextromoramide/therapeutic use , Dose-Response Relationship, Drug , Droperidol/therapeutic use , Dyskinesia, Drug-Induced/etiology , Female , Humans , Infant , Male , Neuroleptanalgesia/adverse effects , Neuromuscular Nondepolarizing Agents/therapeutic use , Tranquilizing Agents/adverse effectsABSTRACT
A glucid-lipid and protein compound nutriment: Trive 1000 was administered to 53 patients during the first three postoperative days in varying doses: -1.000 ml per day to a first group -1.500 ml per day to a second group. The local tolerance was quite good. However, a few accidents of a general character were noted: they were due to a great extent to a non-observance of the rules of preservation. A study of the glucides, in Sorbitol form, showed a good assimilation of the substratum. Glycemia remaining within normal, no glycosuria or ketonuria could be observed. The assimilation of the proteins seemed on the whole satisfactory. No important rise in the blood urea was noted. Nitrogen balances showed that, thanks to this nutriment, almost half of them were positive during the post-aggressive period. The more important the dose of Trive 1000, the more positive the nitrogen balances were. The administration of lipids did not reveal any significant change in the total lipids, triglycerides or cholesterol. A study of the graphic record of lipid levels showed chylomicrons twice. On the opposite, lipoproteins were hardly modified apart from a significant in pre-beta lipoproteins. The quantitative analysis of amino-acids proved interesting. A comparative study of amino-acids both in blood and urine before and after the administration of Trive 1000 showed very little variations in connection with essential amino-acids. If the proportions in the blood of non-essential amino-acids were comparatively but little modified before and after the treatment, on the oppostie, the urinary clearance rate of the same amino-acids after treatment was far more variable and often quite important as far as certain amino-acids were concerned.
