1.
Eur J Immunogenet
; 31(1): 1-3, 2004 Feb.
Article
in English
| MEDLINE
| ID: mdl-15009173
ABSTRACT
The mouse CD1 system is formed by two closely related genes named Cd1d1 and Cd1d2. Cd1d1 encodes a molecule that presents antigens to NKT cells. The function of the Cd1d2 gene has not been elucidated. Here we described a method to analyse variations in mouse Cd1 genes. We found a new allele for Cd1d2 characterized by a point mutation, resulting in a replacement of alanine at position 176 by a valine.