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1.
J Neuroeng Rehabil ; 15(1): 36, 2018 05 08.
Article in English | MEDLINE | ID: mdl-29739468

ABSTRACT

The original article [1] contains a small mistake concerning the ARTIC Team members mentioned in the Acknowledgements. The team member, Rocco Salvatore Calabrò had their name presented incorrectly. This has now been corrected in the original article.

2.
J Environ Radioact ; 166(Pt 2): 382-389, 2017 Jan.
Article in English | MEDLINE | ID: mdl-27158059

ABSTRACT

The indoor radon concentration was measured in most houses in a couple of municipalities in Austria. At the same time the activity concentration of radium in soil, the soil gas radon concentration, the permeability of the ground and the ambient dose equivalent rate were also measured and the geological situations (geological units) were recorded too. From the indoor radon concentration and different house and living parameters a radon potential (Austrian radon potential) was derived which should represent the radon concentration in a standard room. Another radon potential (Neznal radon potential) was calculated from the soil gas radon concentration and the permeability. The aim of the investigation was to correlate all the different variables and to test if the use of surrogate data (e.g. geological information, ambient dose equivalent rate, etc.) can be used to judge the radon risk for an area without performing numerous indoor measurements.


Subject(s)
Air Pollutants, Radioactive/analysis , Air Pollution, Indoor/statistics & numerical data , Geology , Radiation Monitoring , Austria , Radon/analysis
3.
Radiat Prot Dosimetry ; 162(1-2): 78-82, 2014 Nov.
Article in English | MEDLINE | ID: mdl-25013031

ABSTRACT

According to Austrian Law, dose assessments in workplaces with potentially enhanced radon exposures are mandatory since 2008, including tourist mines and caves. A pilot study was carried out to evaluate the situation to test the measurement methods and to specify the main parameters controlling the radon concentration in tourist mines and caves. Radon was measured in six mines and three caves for 1 y, along with determining thoron and equilibrium factors and taking into account climatic, geological and site-related effects. The radon concentrations have a seasonal dependence with maximum in summer and minimum in winter, related to natural ventilation. Radon concentrations in the karst caves were quite low, as it was in the salt mine, whereas radon concentrations in copper and silver mines were high. The dose assessment of the employees yielded doses above 6 mSv a(-1) only in the copper mine.


Subject(s)
Air Pollutants, Radioactive/analysis , Caves , Mining , Occupational Exposure/analysis , Radiation Monitoring , Radiation Protection , Radon/analysis , Austria , Humans , Pilot Projects
4.
Brain Res ; 879(1-2): 183-7, 2000 Oct 06.
Article in English | MEDLINE | ID: mdl-11011020

ABSTRACT

Mutant Cu/Zn superoxide dismutase (SOD1) associated with familial amyotrophic lateral sclerosis (FALS) causes selective motor neuron loss through unknown mechanisms of cell damage. Damaged neurons frequently undergo apoptosis mediated by the p53 cell survival regulator. We therefore studied whether motor neuron disease (MND) in mice expressing the human SOD1 mutant G93A is dependent on p53 by crossing G93A mice with p53-knockout mice. Since p53-/- mice's life expectance is usually shorter (160+/-49 days, n=11) than the time at which the G93A mice die from MND (212+/-50 days, n=7), only a few of the G93A/p53-/- double transgenics were expected to live to experience MND. Nevertheless, four of the 22 G93A/p53-/- mice succumbed to MND after 160+/-28 days, as expected under these conditions of competing death risks if the absence of p53 fails to protect from MND. Thus, MND in mice expressing G93A does not require p53. This conclusion is supported by histology: pre-symptomatic G93A mice display disease-associated vacuoles within the dendrites of motor neurons regardless of p53 status.


Subject(s)
Genes, p53 , Motor Neuron Disease/pathology , Motor Neurons/pathology , Spinal Cord/pathology , Superoxide Dismutase/genetics , Tumor Suppressor Protein p53/physiology , Aging , Amino Acid Substitution , Animals , Crosses, Genetic , Disease Models, Animal , Humans , Lumbar Vertebrae , Mice , Mice, Knockout , Mice, Transgenic , Motor Neuron Disease/genetics , Superoxide Dismutase/deficiency , Tumor Suppressor Protein p53/deficiency , Tumor Suppressor Protein p53/genetics
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