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2.
Proteomics ; 13(20): 2938-41, 2013 Oct.
Article in English | MEDLINE | ID: mdl-24108682

ABSTRACT

The HUPO Brain Proteome Project (HUPO BPP) held its 19th workshop in Dortmund, Germany, from May 22 to 24, 2013. The focus of the spring workshop was on strategies and developments concerning early diagnosis of neurodegenerative diseases.


Subject(s)
Biomarkers/cerebrospinal fluid , Biomedical Research , Brain/pathology , Early Diagnosis , Neurodegenerative Diseases/diagnosis , Proteome/metabolism , Proteomics , Animals , Brain/metabolism , Humans , Magnetic Resonance Imaging , Mice , Neurodegenerative Diseases/cerebrospinal fluid , Rats
3.
Proteomics ; 13(2): 210-6, 2013 Jan.
Article in English | MEDLINE | ID: mdl-23341064

ABSTRACT

The HUPO Brain Proteome Project (HUPO BPP) held its 17(th) workshop in Sao Paulo, Brazil, on May 24 and 25, 2012. The focus was on the progress on the Human Brain Proteome Atlas as well as ideas, strategies and methodological aspects in clinical neuroproteomics.


Subject(s)
Biomarkers/analysis , Brain Chemistry , Nerve Tissue Proteins/analysis , Proteome/analysis , Proteomics/methods , Animals , Biomedical Research , Humans
4.
Proteomics ; 13(2): 217-8, 2013 Jan.
Article in English | MEDLINE | ID: mdl-23341065

ABSTRACT

The HUPO Brain Proteome Project (HUPO BPP) held its 18(th) workshop in Boston, USA, September 12(th) 2012 during the HUPO 11th Annual Word Congress. The focus was on the progress on the Human Brain Proteome Atlas as well as ideas, strategies and methodological aspects.


Subject(s)
Nerve Tissue Proteins/analysis , Neurodegenerative Diseases/metabolism , Proteome/analysis , Proteomics/methods , Biomedical Research , Brain Chemistry , Humans
5.
Proteomics ; 12(3): 356-8, 2012 Feb.
Article in English | MEDLINE | ID: mdl-22290803

ABSTRACT

The HUPO Brain Proteome Project (HUPO BPP) held its 16th workshop in Geneva, Switzerland, on September 5, 2011 during the 10th HUPO World Congress. The focus was on launching the Human Brain Proteome Atlas as well as ideas, strategies and methodological aspects in clinical neuroproteomics.


Subject(s)
Neurodegenerative Diseases/metabolism , Proteomics , Translational Research, Biomedical/methods , Brain/metabolism , Humans
6.
Proteomics ; 11(22): 4279-83, 2011 Nov.
Article in English | MEDLINE | ID: mdl-22045679

ABSTRACT

The HUPO Brain Proteome Project (HUPO BPP) held its 15th workshop in Bochum, Germany, from April 8th to 9th, 2011 directly after the Proteomic Forum 2011 in Berlin. Like on every spring workshop, the focus was more on clinical aspects, so that especially clinicians participated in this workshop.


Subject(s)
Neurodegenerative Diseases/metabolism , Animals , Brain/metabolism , Humans , Proteome/metabolism
7.
Proteomics ; 11(14): 2759-62, 2011 Jul.
Article in English | MEDLINE | ID: mdl-21717571

ABSTRACT

The HUPO Brain Proteome Project (HUPO BPP) held its 13th workshop in Ochang from March 30th to 31st, 2010 prior to the Korean HUPO 10th Annual International Proteomics Conference. The principal aim of this project is to obtain a better understanding of neurodiseases and aging with the ultimate objective of discovering prognostic and diagnostic biomarkers, in addition to the development of novel diagnostic techniques and new medications. The attendees came together to discuss progress in the clinical neuroproteomics of human and to define the needs and guidelines required for more advanced proteomics approaches.


Subject(s)
Atlases as Topic , Brain Chemistry , Brain/metabolism , Congresses as Topic , Proteome , Proteomics/methods , Biomarkers/metabolism , Computational Biology/methods , Humans , Republic of Korea
8.
Proteomics ; 11(16): 3269-72, 2011 Aug.
Article in English | MEDLINE | ID: mdl-21796782

ABSTRACT

The HUPO Brain Proteome Project (HUPO BPP) held its 14th workshop during the HUPO 9th Annual World Congress in Sydney, Australia. The principal aim of this project is to discover prognostic and diagnostic biomarkers associated with neurodegenerative diseases and brain aging, with the ultimate objective of obtaining a better understanding of these conditions and creating roads for the development of novel diagnostic techniques and effective treatments. The attendees came together to discuss progress in the human clinical neuroproteomics and to define the needs and guidelines required for more advanced proteomics approaches.


Subject(s)
Brain/metabolism , Neurodegenerative Diseases/metabolism , Proteome/metabolism , Proteomics , Atlases as Topic , Brain Chemistry , Databases, Protein , Humans
9.
Methods Mol Biol ; 696: 235-46, 2011.
Article in English | MEDLINE | ID: mdl-21063951

ABSTRACT

Several projects were initiated by the Human Proteome Organisation (HUPO) focusing on the proteome analysis of distinct human organs. The initiative dedicated to the brain, its development and correlated diseases is the HUPO Brain Proteome Project (HUPO BPP). An objective data submission, storage, and reprocessing strategy have been established with the help of the results gained in a pilot study phase and within subsequent studies. The bioinformatic relevance of the data is drawn from the inter-laboratory comparisons as well as from the recalculation of all data sets submitted by the different groups. In the following, results of the single groups as well as the centralised reprocessing effort are summarised, demonstrating the added-value of this concerted work.


Subject(s)
Brain/metabolism , Cooperative Behavior , Data Mining , Laboratories , Proteome/metabolism , Proteomics/methods , Databases, Protein , Humans , Pilot Projects
10.
Proteomics ; 10(11): 2071-3, 2010 Jun.
Article in English | MEDLINE | ID: mdl-20514650

ABSTRACT

The HUPO Brain Proteome Project (HUPO BPP) held its 12th workshop in Toronto on 26 September 2009 prior to the HUPO VIII World Congress. The principal aim of this project is to obtain a better understanding of neurodiseases and ageing, with the ultimate objective of discovering prognostic and diagnostic biomarkers, in addition to the development of novel diagnostic techniques and new medications. The attendees came together to discuss progress in the human clinical neuroproteomics and to define the needs and guidelines required for more advanced proteomic approaches.


Subject(s)
Brain/metabolism , Proteomics/methods , Brain/pathology , Canada , Humans , Neurodegenerative Diseases/metabolism
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