ABSTRACT
We report a new case of lymphangioleiomyoma in a 29 years old woman, with antecedents of recurrent spontaneous pneumothorax; she was diagnosed 2 years previously of retroperitoneal hemangiopericytoma, and she has admitted to the hospital because pneumothorax, chilotorax and honeycomb lung pattern, which induce to review the previous retroperitoneal biopsy and confirm to answer with lymphangioleiomyoma. The literature is reviewed.
Subject(s)
Lung Neoplasms , Lymphangiomyoma , Neoplasms, Multiple Primary , Retroperitoneal Neoplasms , Adult , Female , Humans , Lung Neoplasms/diagnosis , Lymphangiomyoma/diagnosis , Neoplasms, Multiple Primary/diagnosis , Retroperitoneal Neoplasms/diagnosisABSTRACT
OBJECTIVES: The difficulties encountered in making the differential diagnosis and the highly malignant nature of leiomyosarcoma of the bladder, an uncommon tumor type, have prompted us to report on these two cases. MATERIAL AND METHODS: Two cases of leiomyosarcoma of the bladder are described: a 64-year-old female that was treated sequentially by TUR and chemotherapy and died of metastatic disease after 14 months, and an 81-year-old male with metastasis at the time of diagnosis. The literature is reviewed and the clinical pathological immunohistochemical features and treatment are discussed. CONCLUSIONS: The differential diagnosis of this tumor type is complex and requires immunohistochemical data. The diagnosis of leiomyosarcoma is confirmed by the expression of myogenic antigens. Historically, patient survival has been poor and management has been based upon information obtained from a relatively small number of cases with diverse treatment regimens. Because the efficacy of chemotherapy and radiotherapy remains unclear, the treatment of choice is by radical cystectomy or partial cystectomy when tumor location and size permit.
Subject(s)
Leiomyosarcoma , Urinary Bladder Neoplasms , Aged , Aged, 80 and over , Female , Humans , Leiomyosarcoma/diagnosis , Leiomyosarcoma/therapy , Male , Middle Aged , Urinary Bladder Neoplasms/diagnosis , Urinary Bladder Neoplasms/therapyABSTRACT
OBJECTIVES: Adrenal hemangiomas are rare tumors that are difficult to diagnose preoperatively. A case of retroperitoneal hemorrhage arising from adrenal hemangioma is described. This uncommon clinical manifestation prompted us to report on the present case and briefly review the scant literature on the diagnostic and therapeutic aspects. METHODS: The case described herein is that of a male patient who presented with hematoma in scrotum and penis that had appeared progressively with no previous trauma. The diagnosis was made by abdominal US and CT, which showed a retroperitoneal mass that appeared to be solid. An enlarged adrenal gland with tumoral "blush" was shown on selective vascular evaluation. RESULTS: En bloc excision of the adrenal gland, left kidney and spleen was performed. The histological analysis revealed adrenal hemangioma. CONCLUSIONS: Adrenal hemangioma is a rare tumor type with no clinical or biological symptoms of a functioning tumor that is generally diagnosed with difficulty preoperatively. The differential diagnosis must be made to distinguish adenoma, carcinoma, nonfunctioning adrenal pheochromocytoma and spontaneous hemorrhage.
