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1.
Genetika ; 39(12): 1693-7, 2003 Dec.
Article in Russian | MEDLINE | ID: mdl-14964838

ABSTRACT

Associations between some characteristics of fitness (the age of the first reproduction, life span, fertility, and number of missed pregnancies) and heterozygosity for some allozyme loci have been studied in a population of the sable Martez zibellinna L. kept in cages at a farm. Of all fitness characteristic studied, a weak correlation has only been found between heterozygosity and the age of the first reproduction (maturation rate). The age of the first reproduction is positively associated with the life span and fertility. The results obtained are discussed in terms of the relationship between the genetic variation of longevity and developmental rate and prospects of their application to breeding practice.


Subject(s)
Carnivora/genetics , Heterozygote , Animals , Fertility/genetics , Life Expectancy
2.
Farmakol Toksikol ; 49(2): 56-9, 1986.
Article in Russian | MEDLINE | ID: mdl-3709776

ABSTRACT

The effect of phenibut on cardiodynamics in 6-7-week-old rats and 14-16-week-old rats with spontaneous, renal and situational hypertension was studied in a 14-day chronic experiment. Phenibut in doses of 25 (young rats) and 50 (adult rats), mg/kg orally was found to exert the pressor effect in the first week and the hypotensive effect in the second week. In both age groups of rats with situational hypertension phenibut decreased arterial blood pressure.


Subject(s)
Aging/drug effects , Heart/drug effects , Hemodynamics/drug effects , Hypertension/drug therapy , gamma-Aminobutyric Acid/analogs & derivatives , Animals , Dose-Response Relationship, Drug , Drug Evaluation, Preclinical , Heart/physiopathology , Hypertension/physiopathology , Hypertension, Renal/drug therapy , Hypertension, Renal/physiopathology , Male , Rats , Rats, Inbred SHR , Stress, Psychological/drug therapy , Stress, Psychological/physiopathology , Time Factors , gamma-Aminobutyric Acid/therapeutic use
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