Subject(s)
Desensitization, Immunologic/methods , Egg Hypersensitivity/therapy , Eggs , Adolescent , Child , Child, Preschool , Female , Humans , Immunoglobulin E/blood , Male , Prospective StudiesABSTRACT
No disponible
Subject(s)
Humans , Male , Child , Respiratory Tract Diseases/epidemiology , Respiratory Tract Diseases/prevention & control , Catheterization , Asthma/diagnosis , Asthma/epidemiology , Albuterol/therapeutic use , Sensitivity and Specificity , Spirometry/trends , Spirometry , Pulmonary Artery/pathology , Pulmonary ArterySubject(s)
Arteriovenous Malformations/diagnosis , Asthma/diagnosis , Lung/pathology , Pulmonary Artery/abnormalities , Respiratory Tract Infections/diagnosis , Animals , Arteriovenous Malformations/complications , Arteriovenous Malformations/pathology , Arteriovenous Malformations/physiopathology , Asthma/complications , Asthma/pathology , Asthma/physiopathology , Child , Cough , Diagnosis, Differential , Fever , Humans , Lung/diagnostic imaging , Magnetic Resonance Angiography , Male , Pulmonary Artery/diagnostic imaging , Pyroglyphidae/immunology , Radionuclide Imaging , Respiratory Tract Infections/etiology , Respiratory Tract Infections/pathology , Respiratory Tract Infections/physiopathology , Spirometry , Tomography, X-Ray ComputedABSTRACT
We present 10 cases (6 males and 4 females) of children aged 4 to 12 years, who were diagnosed with allergy to clavulanic acid (CL) and treated in the Paediatric Allergy Section of the University Hospital Dr. Peset in Valencia from 2000 to 2005. The children reported symptoms of urticaria and angio-oedema after receiving orally-administered amoxicillin/clavulanic acid (A-CL) for an infection. Diagnosis was based on the confirmation of an IgE-mediated aetiology by an oral challenge test with amoxicillin-clavulanic acid. Following negative skin test results and CAP for penicilloyl G and V, amoxicillin, ampicillin and cefaclor < 0.35 KU/l, those patients who were allergic to clavulanic acid (positive oral challenge test) were shown to be tolerant to orally-administered Cefuroxime axetil.
Subject(s)
Anti-Bacterial Agents/adverse effects , Clavulanic Acid/adverse effects , Drug Hypersensitivity/diagnosis , Administration, Oral , Anti-Bacterial Agents/immunology , Child , Child, Preschool , Clavulanic Acid/immunology , Drug Hypersensitivity/immunology , Female , Humans , Immunoglobulin E/blood , Male , Retrospective Studies , Skin TestsABSTRACT
We present 10 cases (6 males and 4 females) of children aged 4 to 12 years, who were diagnosed with allergy to clavulanic acid (CL) and treated in the Paediatric Allergy Section of the University Hospital Dr. Peset in Valencia from 2000 to 2005. The children reported symptoms of urticaria and angio-oedema after receiving orally-administered amoxicillin/clavulanic acid (A-CL) for an infection. Diagnosis was basedon the confirmation of an IgE-mediated aetiology byan oral challenge test with amoxicillin-clavulanic acid. Following negative skin test results and CAP for penicilloy lG and V, amoxicillin, ampicillin and cefaclor< 0.35 KU/l, those patients who were allergic to clavulanic acid (positive oral challenge test) were shown to be tolerant to orally-administered Cefuroximeaxetil
No disponible
Subject(s)
Humans , Male , Female , Child , Hypersensitivity/complications , Hypersensitivity/diagnosis , Clavulanic Acid/adverse effects , Cefuroxime/administration & dosage , Cefuroxime/therapeutic use , Patch Tests/methods , Urticaria/chemically induced , Urticaria/therapy , Retrospective StudiesSubject(s)
Abnormalities, Multiple/diagnosis , Lung/abnormalities , Child , Humans , Lung Diseases/etiology , MaleABSTRACT
No disponible
Subject(s)
Male , Infant, Newborn , Humans , Lung/abnormalities , Respiratory Insufficiency/congenital , Down Syndrome/complications , Trisomy/diagnosis , Radiography, Thoracic , Respiratory Insufficiency/diagnosis , Respiratory Insufficiency , Magnetic Resonance Angiography/methodsABSTRACT
No disponible
Subject(s)
Female , Child , Humans , Bronchopulmonary Sequestration/complications , Bronchopulmonary Sequestration/diagnosis , Bronchopulmonary Sequestration/surgery , Radiography, Thoracic/methods , Angiography/methods , Chest Pain/diagnosis , Diagnosis, Differential , Pneumonia/complications , Respiratory System Abnormalities/physiopathology , Respiratory System Abnormalities , Leukocytosis/complications , Respiratory System Abnormalities/complications , Lung Diseases, Interstitial/complicationsABSTRACT
BACKGROUND: most patients use their inhalers incorrectly and recent asthma management clinical guidelines recommend demonstrating skills and correcting performance at each asthma follow-up visit. However, this statement is poorly evidence-based and few intervention studies have assessed quantitatively the effectiveness of this recommendation. METHODS: from a total of 3,076 children and adolescents with asthma attending an outpatient clinic, a random, representative sample of 255 was obtained and assessed at baseline with a standardised questionnaire regarding their skills when using one of three inhaler devices: pressurised direct aerosol (PDA), dry powder (DP) and aerosol pressurised in expanded camera (APEC). Structured sessions of correct use and handling of inhalers were offered and a new assessment was undertaken after an average of 10.5 months (SD 4.5). RESULTS: only 142 asthmatics maintained the same inhaler device during the study period. An increase of correct manoeuvres was observed for all three devices, and the relative risk and 95% confidence interval (RR and 95% CI) of incorrect post-intervention use was 0.23 (95% CI 0.10-0.56) for PDA, 0.59 (95% CI 0.38-0.92) for DP, and 0.54 (95% CI 0.32-0.90) for APEC. A multivariate analysis indicates that this improvement was observed irrespective of gender and age interval, and that it was even better when parents cooperated with medical and nursing staff. CONCLUSIONS: a dramatic improvement in correct manoeuvres with any of three inhaler devices after active performance training was observed. This easy, highly effective, low cost (in terms of time and personnel) intervention should be routinely implemented in any control visit of asthmatics, leading to a better management of asthma.
Subject(s)
Asthma/drug therapy , Nebulizers and Vaporizers , Patient Education as Topic/methods , Administration, Inhalation , Adolescent , Adult , Child , Child, Preschool , Female , Humans , MaleABSTRACT
Conflict almost completely destroyed Rwanda's infrastructure in 1994. Natural disasters, as well as disasters caused by humans, have severely challenged humanitarian aid available within the country. In this study, we have analysed the experiences of nongovernmental organizations since the summer of 1994 to evaluate how these difficulties may be overcome. One of the problems identified has been restrictions on the ability to introduce effective health planning due to the poor quality of available local information. The implementation of effective plans that show due consideration to the environment and society is clearly necessary. Effective monitoring and detailed observation are identified as being essential to the continuity of existing humanitarian assistance.
Subject(s)
Altruism , Community Health Services/organization & administration , Disasters , Humans , Refugees , Rwanda , Warfare , WorkforceABSTRACT
OBJECTIVE: The aim of this study was to evaluate the efficacy of treatment of asthmatic children by inhalation. PATIENTS AND METHODS: Two hundred twenty-seven young patients have taken part in a practical inquiry regarding the handling of their inhalation device and showing how they attained the appropriate dosage of medicine by using either the direct pressurized aerosol, the dry powder device or pressurized aerosol in an expansion chamber. Five different steps have been observed in the handling of the above mentioned devices. After assembling the data, a profile has been compiled (through absolute and relative frequencies and a 95% confidence interval) and a logistic regression multivariant analysis. RESULTS: Correct handling was observed in 37.2% of the children who used the dry powder device, 51.2% in the children who used the direct pressurized aerosol and 58.6% of those who used the expansion chamber aerosol. The influence of the duration of the treatment plus the age of the patient was also taken into consideration. CONCLUSIONS: From this study it follows that the direct pressurized aerosol treatment and the dry powder device are incorrectly handled by a high percentage of children and this problem gets worse as the age of the patient increases. In contrast, the proportion of children who use correctly the expansion chamber aerosol is highest and remains similar for all age groups. Misusage increases when the explanation of the treatment is provided by the parents and also when the treatment occurs for a period greater than 22 months without reminding the patient of the correct usage of the apparatus.
