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J Clin Pharm Ther ; 43(1): 107-109, 2018 Feb.
Article in English | MEDLINE | ID: mdl-28646522

ABSTRACT

WHAT IS KNOWN AND STUDY OBJECTIVE: Infliximab is a widely used drug for treating inflammatory bowel disease (IBD). This drug is known to rarely cause pericarditis in adult populations. CASE SUMMARY: This report details the case of a 14-year-old boy with ulcerative colitis who developed pericarditis after a second infliximab infusion. After discontinuation of therapy, the patient's symptoms were resolved. WHAT IS NEW AND CONCLUSION: To our knowledge, this is the first reported paediatric case of pericarditis as a possible complication of infliximab therapy in IBD. Among infliximab-related delayed adverse reactions, cardiac complications should be monitored in the paediatric population.


Subject(s)
Colitis, Ulcerative/drug therapy , Infliximab/adverse effects , Infliximab/therapeutic use , Pericarditis/chemically induced , Adolescent , Humans , Inflammatory Bowel Diseases/drug therapy , Male
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