[An immunoenzyme method for determining the O-antigen of Sonne's shigella with the use of affinity isolated antibodies]. / Immunofermentnyi metod opredeleniia O-antigena shigell Zonne s ispol'zovaniem affinno vydelennykh antitel.

The sensitivities of ELISA systems for assays of Shigella sonnei O-antigen, developed on the basis of specific rabbit antibodies isolated from antisera by different chromatography techniques have been compared. The highest specificity and sensitivity of O-antigen determination (0.5-1 ng/ml) is achieved when using affinity-isolated antibodies to O-antigen. Clinical trials of this ELISA system have been carried out.