ABSTRACT
INTRODUCTION: Pseudolymphomatous folliculitis (PLF) is a rare benign cutaneous lymphoid hyperplasia that most commonly occurs in the facial region as a dome-shaped or flat elevated nodule. MATERIALS AND METHODS: We studied the clinicopathologic and immunohistochemical characteristics of 19 cases of PLF. RESULTS: The patients comprised 11 females and eight men (mean age 44.9; age range 9-77 years). All cases were solitary except one case with multiple lesions. The lesions were located in the facial region except one that was located in the back. Histologically, there was a diffuse or nodular lymphoid infiltrate with hyperplastic and distorted hair follicles and occasionally enlarged eccrine units with a clear nuclear morphology. Immunohistologically, three cases showed predominantly B-cells, eight cases predominantly B-cells with numerous T-cells, six cases predominantly T-cells with numerous B-cells, and two cases predominantly T-cells. All lesions showed increased numbers of perifollicular dendritic cells expressing anti-S-100 protein and CD1a. DISCUSSION: PLF is a rare, benign, cutaneous lymphoid hyperplasia that may resemble cutaneous lymphoma. It has characteristic clinical and pathologic features showing abundant periadnexal S-100/CD1a -positive dendritic cells with dilated and activated pilosebaceous units. The lesion may resolve with complete excision or present spontaneous regression.
ABSTRACT
BACKGROUND: liposarcoma is a malignant tumor of soft tissue and the most common sarcoma in the adult life. The myxoid liposarcoma accounts for 30 to 35 % of all liposarcomas. It is commonly seen on the thighs. Only two cases in which the liposarcoma was found in the vertebral column have been reported. CLINICAL CASE: this is a 28 year old woman with symptoms of spinal cord injury by compression (tottering gait, weakness 4/5 and decreased sensibility in right leg). The MRI showed a right paravertebral multinodular mass from L4 to S2, with solid and cystic aspects, following the S1 and S2 intervertebral foramen to the presacral space, with low signal intensity on T1 and high on T2. The diagnosis of neurofibroma was concluded. The patient was scheduled for surgery. Extra and intraspinal excision was performed and a mass was removed. Histopathologic study reported myxoid liposarcoma. CONCLUSIONS: liposarcoma is a malignant tumor of soft tissues. The spine is a rare location for this neoplasm, even for metastases. It is difficult to achieve a complete resection in this localization, so the recurrence rate is high.
Introducción: el liposarcoma es un tumor maligno de tejidos blandos que constituye el grupo más numeroso de sarcomas en el adulto. La variante mixoide representa 30 a 35 % de todos los liposarcomas. Comúnmente se observa en los muslos. En la literatura se han informado solo dos pacientes con liposarcoma en la columna vertebral. Caso clínico: mujer de 28 años de edad con síntomas de compresión medular (marcha claudicante, fuerza en la extremidad derecha 4/5, disminución de la sensibilidad). La imagen por resonancia magnética confirmó una masa paravertebral derecha que se extendía desde L4 hasta S2, multinodular, sólido quística, que seguía el trayecto de los forámenes de conjunción de S1 y S2 hacia el espacio presacro, con señales hipointensas en T1 e hiperintensas en T2. Con los estudios radiológicos se concluyó que presentaba un neurofibroma. Se realizó resección extra e intrarraquídea, de la que se extrajo un tumor. El estudio histopatológico definitivo indicó que se trataba de un liposarcoma mixoide. Conclusiones: la columna vertebral es una localización poco frecuente para esta neoplasia, así como para sus metástasis. Es difícil lograr una resección completa en este sitio, por lo que la tasa de recurrencia es alta.
Subject(s)
Liposarcoma, Myxoid , Lumbar Vertebrae , Spinal Neoplasms , Adult , Female , Humans , Liposarcoma, Myxoid/diagnosis , Liposarcoma, Myxoid/surgery , Spinal Neoplasms/diagnosis , Spinal Neoplasms/surgeryABSTRACT
Hepatic angiosarcoma is a malignant mesenchymal neoplasm of endothelial cells of high grade. Hepatic angiosarcoma represents two percent of all primary neoplasm liver. The highest incidence is between the sixth and seventh decade of life, youth and children is rare, predominantly in men (3:1). Most are idiopathic (75 %). Diagnosis is difficult because clinical manifestations and imaging studies are inconclusive. When clinical manifestations begin progression is often fast, and possibilities for curative treatment are limited. We report the case of a man aged 17, presented two clinical episodes of hemoperitoneum with ultrasound and CT diagnosis of hepatic hemangioma, hepatectomy was performed in the right lobe, the histological study reported multicenter liver angiosarcoma.