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1.
Am Heart J Plus ; 34: 100310, 2023 Oct.
Article in English | MEDLINE | ID: mdl-38510948

ABSTRACT

Background: We developed a three-pronged complex intervention to improve selfcare and deliver whole person care for patients with heart failure, underpinned by the 'extant cycle' theory - a theory based on our formative work. Methods: This is a 3 centre, 2-arm, 1:1, open, adaptive stratified, randomized controlled trial. We included patients aged ≥ 18 years with heart failure, taking any of the key guideline directed medical treatments, with a history of or currently on a high ceiling diuretic. We excluded end stage renal disease, clinically diagnosed severe mental illness or cognitive dysfunction and having no caregivers. Interventions included, (i) trained hospital based lay health worker mediated assessment of patients' current selfcare behaviour, documenting barriers and facilitators and implementing a plan to 'transition' the patient toward optimal selfcare. (ii) m-health mediated remote monitoring and (iii) dose optimization through a 'physician supervisor'. Results: We recruited 301 patients between Jan 2021 and Jan 2022. Mean age was 59.8 (±11.7) years, with 195 (64.8 %) from rural or semi-urban areas and 67.1 % having intermediate to low health literacy. 190 (63.1 %) had an underlying ischemic cardiomyopathy. In the intervention arm, 142 (94.1 %) had a Selfcare in Heart Failure Index (SCHFI) score of ≤70, with significant barriers being 'lack of knowledge' 105 (34.5 %) and 'behavioural passivity' 23 (7.5 %). Conclusion: This is the first South Asian trial evaluating a complex intervention underpinned by behaviour change theory for whole person heart failure care. These learnings can be applied to heart failure patient care in other resource constrained health systems.

2.
Wellcome Open Res ; 5: 10, 2020.
Article in English | MEDLINE | ID: mdl-32266322

ABSTRACT

Background: Adherence to a complex, yet effective medication regimen improves clinical outcomes in patients with chronic heart failure (CHF). However, patient adherence to an agreed upon plan for medication-taking is sub-optimal and continues to hover at 50% in developed countries. Studies to improve medication-taking have focused on interventions to improve adherence to guideline-directed medication therapy, yet few of these studies have integrated patients' perceptions of what constitutes effective strategies for improved medication-taking and self-care in everyday life. The purpose of this formative study was to explore patient perceived facilitators of selfcare and medication-taking. Methods: We conducted in-depth interviews of patients with long standing heart failure admitted to the cardiology and internal medicine wards of a South Indian tertiary care hospital. We purposively sampled using the following criteria: sex, socio-economic status, health literacy and patient reported medication adherence in the month prior to hospitalization. We employed inductive coding to identify facilitators. At the end of 15 interviews (eight patients and seven caregivers; seven patient-caregiver dyads), we arrived at theoretical saturation for facilitators. Results: Facilitators could be classified into intrinsic (patient traits - situational awareness, self-efficacy, gratitude, resilience, spiritual invocation and support seeking behavior) and extrinsic (shaped by the environment - financial security and caregiver support, company of children, ease of healthcare access, trust in provider/hospital, supportive environment and recognizing the importance of knowledge). Conclusions: We identified and classified a set of key patient and caregiver reported self-care facilitators among Indian CHF patients. The learnings from this study will be incorporated into an intervention package to improve patient engagement, overall self-care and patient-caregiver-provider dynamics.

3.
Am J Crit Care ; 10(1): 4-10, 2001 Jan.
Article in English | MEDLINE | ID: mdl-11153183

ABSTRACT

BACKGROUND: Depressive symptoms are an independent risk factor for outcome in patients with cardiac disease, but their effect on outcome among patients undergoing coronary artery bypass grafting is not well understood. OBJECTIVES: To determine whether or not clinical variables including length of stay, readmission rates, and mortality are related to patients' level of depressive symptoms before and after coronary artery bypass grafting. METHODS: An observational, longitudinal design was used. The Medical Outcomes Study 36-item short-form health survey was used to collect data on depressive symptoms in 416 patients undergoing coronary artery bypass grafting. The distribution of depressive symptoms was correlated with length of stay after the procedure, readmission, and mortality. RESULTS: The level of depressive symptoms before coronary artery bypass grafting correlated with the level of depressive symptoms at 6 weeks follow-up, both for the individual items "feeling down in the dumps" (r = 0.24, P = .009) and "feeling downhearted" (r = 0.36, P < .001) and for the overall score on the Mental Health scale (r = 0.40, P < .001). Feeling down in the dumps (P = .007) and overall scores on the Mental Health scale (P = .02) were significantly related to readmission within 6 months. CONCLUSIONS: Higher levels of depressive symptoms before coronary artery bypass grafting are related to higher hospital readmission rates 6 months after the procedure. Nurses can play a pivotal role in determining which patients require evaluation, educating patients, and initiating effective treatment, which may prevent readmission related to depressive symptoms.


Subject(s)
Coronary Artery Bypass/psychology , Coronary Disease/psychology , Coronary Disease/surgery , Depression/complications , Aged , Confounding Factors, Epidemiologic , Coronary Disease/mortality , Female , Health Surveys , Humans , Length of Stay , Longitudinal Studies , Male , Middle Aged , Observation , Patient Readmission , Risk Factors , Surveys and Questionnaires , Treatment Outcome
4.
Crit Care Nurs Clin North Am ; 13(4): 605-15, 2001 Dec.
Article in English | MEDLINE | ID: mdl-11778347

ABSTRACT

If there is a story waiting to be told about nurses and research, it is this: research is part of our past, our present, and our future. Research gives "caring" a mental muscle that makes it stronger than caring would be without it. Since the Crimean War, research has been a foundational cornerstone of the profession. Florence Nightingale espoused caring and human touch but not without also observing and measuring important patient outcomes that identified the spread of infection via human contact. As a new generation of nurses emerges, we who have come before might serve them well to role model what we know: that strong research is strong nursing and that obtaining and using evidence in nursing practice results in better outcomes for those patients and families we serve. Is the story waiting to be told your story? Part of the story of nursing waiting to be told is your story. Regardless of why you embarked on your career in nursing and regardless of where your journey has taken you to this point, you are a part of the twenty-first century body of nursing, and your individual contribution is an important one. Listen to your patients with an ear toward measuring and evaluating outcomes. Reflect on the care you provided, the interventions you had to offer, and why. Should something have been different? Could something have been better? Find out ... measure it.


Subject(s)
Nursing Research , Communication , Data Collection , Evidence-Based Medicine , Humans , Outcome Assessment, Health Care
5.
Nurs Clin North Am ; 35(4): 877-95, 2000 Dec.
Article in English | MEDLINE | ID: mdl-11072276

ABSTRACT

Advances in the understanding of acute coronary syndromes have occurred rapidly in the last 5 years and have dramatically changed the way patients are evaluated, diagnosed, and managed. Medical advances, such as antiplatelet and antithrombin agents and growing databases on interventional outcomes have created a new world of therapeutic options for the spectrum of ischemic heart disease. As more options become available, nurses are under increasing pressure to stay abreast of what these options have to offer patients, and which patients benefit most from each therapeutic approach. The purpose of this article is to review the newest therapies for acute coronary syndromes, including GP IIb/IIIa inhibitors, low molecular weight heparins, and direct thrombin inhibitors, and discuss indications and contraindications for each of these therapies. Changes in diagnostic approach using troponin T and I are also presented.


Subject(s)
Coronary Disease , Fibrinolytic Agents , Acute Disease , Clinical Trials as Topic , Coronary Disease/diagnosis , Coronary Disease/drug therapy , Coronary Disease/nursing , Coronary Disease/physiopathology , Fibrinolytic Agents/adverse effects , Fibrinolytic Agents/therapeutic use , Humans
6.
Am J Cardiol ; 85(7): 801-5, 2000 Apr 01.
Article in English | MEDLINE | ID: mdl-10758916

ABSTRACT

We evaluated cardiac troponin T (cTnT) and creatine kinase-MB (CK-MB) for risk stratification of chest pain unit (CPU) patients. We studied 383 consecutive patients with chest pain assigned to our CPU by emergency department physicians. At baseline all had normal or nondiagnostic electrocardiograms, no high-risk clinical features, and negative CK/CK-MB. CK-MB and electrocardiograms were taken at 0, 4, 8, and 12 hours and cTnT at 0, 4, and 8 hours. Eight patients (2.1%) were CK-MB positive and 39 (10.2%) were cTnT positive, including all but 1 CK-MB-positive patient. All marker-positive patients were detected by 8 hours. Seven cTnT-positive patients and 1 cTnT-negative patient had myocardial infarction (p <0.0001). cTnT-positive patients were older, less likely to be women or smokers, and more often had diabetes mellitus or known coronary disease (CAD). Seventy-one percent of patients underwent diagnostic testing. cTnT-positive patients more often underwent angiography (46% vs 20%) and underwent stress testing less often (28% vs 57%) than cTnT-negative patients. When performed, their stress tests were more often positive (46% vs 14%) and they more often had angiographically significant lesions (89% vs 49%) and multivessel disease (67% vs 29%). There were no short-term deaths. Long-term mortality was higher in cTnT-positive patients (27% vs 7%, p <0.0001). Thus, cTnT identified more CPU patients with myocardial necrosis and multivessel CAD than CK-MB and a population with high long-term mortality risk. Routine use of cTnT in CPUs could facilitate risk stratification and management.


Subject(s)
Chest Pain/blood , Coronary Care Units , Creatine Kinase/blood , Myocardium/metabolism , Troponin T/blood , Aged , Biomarkers/blood , Chest Pain/diagnosis , Diagnosis, Differential , Electrocardiography , Female , Humans , Isoenzymes , Male , Middle Aged , Prognosis , Retrospective Studies , Risk Assessment
8.
Prog Cardiovasc Nurs ; 14(1): 25-9, 1999.
Article in English | MEDLINE | ID: mdl-10431316

ABSTRACT

Our Heart Center staff identified a need to become more involved in nursing research and evidence based practice. A lack of awareness of the research process and current Heart Center nursing research studies resulted in low patient enrollment. To overcome these challenges a Heart Center Nursing Research Work Group (HCNRWG) was created with support of management. Staff nurses from each unit within the Heart Center participated, and sessions were facilitated by an Assistant Nurse Manager and Clinical Nurse Specialist. Advanced Practice Nurses functioned as consultants. The goal was to support nurses in developing a greater understanding of research and promote nursing research and visibility. Results included the development of research notebooks, inclusive of medical, nursing, and collaborative research projects, "Ask Me About Nursing Research" buttons, and mechanisms for study enrollment for each unit. Writing workshops were held to assist nurses with the preparation of abstracts, manuscripts, and research. A "hot line" was established to answer questions and informational packets and newsletters were distributed to staff and leadership quarterly. An increased awareness of research among the health care team has ensued. Meeting attendance has tripled, more nursing abstracts have been submitted to national conferences and there are ongoing research studies on all heart center units with increased patient enrollment.


Subject(s)
Education, Nursing, Continuing/organization & administration , Heart Diseases/nursing , Inservice Training/organization & administration , Nursing Research/education , Nursing Research/organization & administration , Nursing Staff, Hospital/education , Nursing Staff, Hospital/organization & administration , Professional Staff Committees/organization & administration , Diffusion of Innovation , Health Knowledge, Attitudes, Practice , Hotlines , Humans , Motivation , Needs Assessment , Nursing Staff, Hospital/psychology , Program Evaluation
9.
Am J Crit Care ; 7(2): 123-30, 1998 Mar.
Article in English | MEDLINE | ID: mdl-9509226

ABSTRACT

BACKGROUND: Methods of converting treatment with i.v. nitroglycerin to treatment with nitroglycerin ointment 2% vary greatly and may affect the length of time patients remain in the ICU, nursing time, and possible recurrent angina. To date, no randomized, controlled studies have evaluated the methods used for conversion. OBJECTIVE: To evaluate two methods of conversion. METHODS: Two hundred patients receiving i.v. nitroglycerin at doses of 10 to 100 micrograms/min were randomized to two methods of conversion: (1) Apply nitroglycerin ointment and stop i.v. nitroglycerin 30 minutes later. (2) Decrease the dose of i.v. nitroglycerin by 10 micrograms/min every 15 minutes, apply one half the dose of nitroglycerin ointment when the original i.v. dose has been decreased by one half, and apply the full dose of the ointment when the i.v. nitroglycerin is stopped. The primary end point was the time patients remained in the ICU after the conversion. Secondary end points included time to hospital discharge, estimate of nursing time, and selected clinical end points. Kaplan-Meier and Cox regression analyses were used to evaluate time patients remained in the ICU and nursing time. Clinical outcomes were analyzed by using a chi-square test. RESULTS: Use of the first method reduced median time before transfer from the ICU by 23 minutes and median nursing time by 45 minutes. Analysis of all clinical outcomes showed no differences between the two methods. CONCLUSIONS: Use of the first method was associated with a reduction in the time patients remained in the ICU before transfer to another unit and savings in nursing time, but the two methods did not differ according to clinical outcomes.


Subject(s)
Angina Pectoris/drug therapy , Nitroglycerin/administration & dosage , Vasodilator Agents/administration & dosage , Administration, Cutaneous , Adult , Aged , Aged, 80 and over , Chi-Square Distribution , Critical Care , Drug Administration Schedule , Female , Humans , Infusions, Intravenous , Male , Middle Aged , Proportional Hazards Models , Prospective Studies , Retrospective Studies , Treatment Outcome
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