ABSTRACT
A study was made of the protective effect of beta-carotine and ephasol against genetic damages in germ cells of male mice, exposed within the zone of Chernobyl NPP or ingested by 137Cs. The analysis of reproductive function, frequencies of dominant lethal mutations, abnormal sperm heads, reciprocal translocations and testis mass decrease show that both agents are more effective in protection against reproductive function damages than against genetic effects.
Subject(s)
Environmental Exposure/adverse effects , Power Plants , Radioactive Hazard Release , Spermatozoa/drug effects , Spermatozoa/radiation effects , Animals , Carotenoids/pharmacology , Cesium Radioisotopes/adverse effects , Male , Mice , Mice, Inbred C57BL , Mice, Inbred CBA , Organ Size/drug effects , Organ Size/radiation effects , Palladium/pharmacology , Radiation-Protective Agents/pharmacology , Testis/drug effects , Testis/radiation effects , Ukraine , beta CaroteneABSTRACT
A study was made of the protective effect of ephasol against genetic damages induced in mice germ cells by single, fractionated and chronic gamma radiation. Study of male reproductive ability, frequency of induced dominant lethal mutations, abnormal sperm heads and reciprocal translocation show that the efficacy of ephasol was higher in condition of chronic exposure.