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Org Biomol Chem ; 10(11): 2227-30, 2012 Mar 21.
Article in English | MEDLINE | ID: mdl-22331171

ABSTRACT

It has been demonstrated in our studies that the intrinsic curvature of DNA can be easily interrupted by low concentrations of chloroquine and ethidium bromide. In addition, the changes of DNA curvature caused by varying the concentration of these two DNA intercalators can be readily verified through using an atomic force microscope.


Subject(s)
DNA/ultrastructure , Plasmids/ultrastructure , DNA/chemistry , Ethidium/chemistry , Microscopy, Atomic Force , Plasmids/chemistry
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