1.
Trends Pharmacol Sci
; 44(11): 755-757, 2023 Nov.
Article
in English
| MEDLINE
| ID: mdl-37679271
ABSTRACT
Aberrant expression of transmembrane mucins promotes tumor progression and interferes with immunological and medicinal elimination of cancer cells. In a recent article, Pedram et al. directed an attenuated bacterial mucin-specific protease to HER2-positive tumor cells and observed decreased tumor growth rates and extended survival of mice bearing HER2-positive tumors.