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3.
Clin Pract Cases Emerg Med ; 2(3): 227-230, 2018 Aug.
Article in English | MEDLINE | ID: mdl-30083639

ABSTRACT

Cor triatriatum is a rare, congenital heart defect. When diagnosis does not occur in infancy, primary symptoms in an older patient may mimic reactive airway disease. We report a case of cor triatriatum in an older child, previously diagnosed with asthma, presenting to an emergency department with a chief complaint of wheezing. Initial treatment with bronchodilators and corticosteroids was unsuccessful, prompting thorough evaluation. Subsequent imaging diagnosed cor triatriatum sinister. When presentations consistent with common conditions, such as asthma, do not respond appropriately to classic intervention, emergency physicians must be prepared to consider alternative and rare diagnosis.

4.
Pediatr Emerg Med Pract ; 15(3): 1-16, 2018 Mar.
Article in English | MEDLINE | ID: mdl-29490126

ABSTRACT

Corticosteroids have been used for over half a century to treat various inflammatory disorders; however, their use in many pediatric conditions remains controversial. This issue reviews evidence on corticosteroid treatment in acute asthma exacerbations, croup, acute pharyngitis, anaphylaxis, acute spinal injury, and bacterial meningitis. While corticosteroids are clearly indicated for management of asthma exacerbations and croup, they are not universally recommended for potential spinal cord injury. Due to insufficient data or conflicting data, corticosteroids may be considered in children with acute pharyngitis, anaphylaxis, and bacterial meningitis.


Subject(s)
Critical Illness/therapy , Emergency Medical Services/methods , Glucocorticoids/therapeutic use , Acute Disease , Adolescent , Anaphylaxis/drug therapy , Asthma/drug therapy , Child , Child, Preschool , Croup/drug therapy , Emergencies , Female , Glucocorticoids/adverse effects , Humans , Male , Meningitis, Bacterial/drug therapy , Pharyngitis/drug therapy , Practice Guidelines as Topic , Spinal Injuries/drug therapy
5.
Ann Vasc Surg ; 21(4): 408-14, 2007 Jul.
Article in English | MEDLINE | ID: mdl-17502133

ABSTRACT

We examined the safety of performing synchronous carotid endarterectomy (CEA) and coronary artery bypass grafting (CABG) in specific groups of patients with coexistent cerebral and coronary vascular disease. Between 1981 and 2003, 8,277 patients who underwent CABG in our institution had noninvasive screening for carotid disease. Two hundred seventy-seven (3.34%) patients were found to have severe (>70%) carotid stenosis. This patient population was divided into three subgroups: group A had unilateral carotid disease (n = 200), group B had bilateral carotid disease (n = 55), and group C had contralateral carotid occlusion (n = 22). In 29 patients (10.4%), the carotid disease was symptomatic. A simultaneous CABG and CEA was performed in all three subgroups. Patients in group B underwent initially repair of the most dominant lesion, soon followed by contralateral CEA. Patients who underwent only CABG (n = 8,000) served as controls. Overall combined hospital mortality regardless of etiology for the combined group was 3.61% vs. 1.7% for the patients who had CABG only (P > 0.1). The stroke and/or myocardial infarction-associated mortality for the simultaneous CEA-CABG group was 2.52%. There were six deaths in group A (3%), two in group B (3.6%), and two in group C (9.09%). Early stroke complicated the course of four (2%) patients in group A, one (1.8%) patient in group B, and three (13.64%) patients in group C compared to a stroke rate of 1.28% in controls. Overall stroke rate in the combined group was 2.8%. History of previous stroke and age 70-80 were the most important predictors of postoperative stroke and death. In the combined surgery group, the postoperative myocardial infarction rate was 0.72% vs. 0.58% in the control group. The mean length of hospital stay was 9 days for patients who had the combined procedure vs. 8.1 days for patients who had CABG only. Use of the combined procedure for patients with concomitant carotid and coronary artery disease was justified in the patients under study.


Subject(s)
Carotid Artery Diseases/epidemiology , Coronary Artery Bypass , Coronary Disease/epidemiology , Endarterectomy, Carotid , Aged , Carotid Artery Diseases/surgery , Comorbidity , Coronary Disease/surgery , Female , Humans , Length of Stay , Male , Morbidity , Risk Factors , Treatment Outcome
6.
Somatosens Mot Res ; 22(3): 127-40, 2005 Sep.
Article in English | MEDLINE | ID: mdl-16338822

ABSTRACT

An ALSCAL multidimensional scaling analysis in Euclidean space revealed that three orthogonal perceptual dimensions can account for the judged tactile dissimilarities of raised-dot patterns. Through magnitude estimates of various perceptual attributes, it was determined that the three dimensions consist of blur, roughness, and clarity. The only effect that selective adaptation of the Pacinian (P) channel had was to change the perceptual clarity of the raised dots against their background. Adaptation of the P channel with a 20 dB SL 250 Hz stimulus enhanced clarity. As indicated by magnitude estimates, adaptation of the P channel by the 250 Hz stimulus had no effect on the perceived roughness of the dot pattern but did cause the individual dots of the textured pattern to feel smoother. When the observer was required to estimate magnitude "overall roughness" defined as a combination of dot-pattern roughness and individual-dot roughness, adaptation of the P channel affected perceived roughness by reducing it. Taken as a whole, the results are consistent with the hypothesis that the NP channels and the P channel jointly influence the perception of textured surfaces.


Subject(s)
Perception/physiology , Touch/physiology , Adaptation, Physiological , Adult , Female , Humans , Male , Physical Stimulation , Vibration
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