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Synthesis and antifungal activity of some amidrazone derivatives.
Vio, L; Mamolo, M G; Ronsisvalle, G; Oliveri, S; Grego, A M.
Farmaco ; 44(9): 819-29, 1989 Sep.
Article in English | MEDLINE | ID: mdl-2690844

ABSTRACT

The synthesis and in vitro antifungal activity of some pyridincarboxyamidrazone derivatives are described. 2-pyridincarboxyamidrazone derivative (IIa) in comparison with miconazole showed an interesting even if low antimycotic activity.


Subject(s)
Amidines/pharmacology , Antifungal Agents/chemical synthesis , Pyridines/pharmacology , Amidines/chemical synthesis , Aspergillus niger/drug effects , Candida albicans/drug effects , Chemical Phenomena , Chemistry , Culture Media , Fungi/drug effects , Furans/chemical synthesis , Furans/pharmacology , Magnetic Resonance Spectroscopy , Microbial Sensitivity Tests , Pyridines/chemical synthesis , Thiophenes/chemical synthesis , Thiophenes/pharmacology , Trichophyton/drug effects
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